Structural biology of virulence in Gram positive bacteria
Structural foundations for non-heme iron enzymes
We have opening for up to 3 postdoctoral associates on 2 projects. For the
virulence project diffraction-quality crystals of several virulence factors
or virulence-associated proteins from pathogenic bacteria have been grown
from recombinant protein. For the metalloenzyme project we have crystals of
several mutant catechol dioxygenases in hand. The postdoctoral associates
will have responsibility for the structural determination and refinement of
Candidates must have a proven background in macromolecular crystallography.
Experience in protein chemistry is also a plus. Applicants must have a
recent Ph.D. in biochemistry, chemistry, molecular biology or a closely
The laboratory is located in on the banks of the Mississippi River in the
Minneapolis campus (http://www.onestop.umn.edu/Access/QTVRmovies/index.html)
of the University of Minnesota. For the past 3 years the University of
Minnesota has been rated as one of the top 3 public research university in
the U.S. (http://thecenter.ufl.edu/). The laboratory is part of Kahlert
Structural Biology Laboratory and has state-of-the-art crystallographic
facilities which are shared with Dr. Len Banaszak and Dr. Carrie Wilmot.
Synchrotron beamtime is available at the ALS through the university's
membership in the Molecular Biology Consortium (http://www.mbc-als.org/).
Outstanding computational resources are available through the Minnesota
Supercomputing Institute (http://www.msi.umn.edu/) which maintains the Basic
Sciences Computing Laboratory (http://www.msi.umn.edu/bscl/hardware/)
adjacent to the Kahlert Structural Biology Laboratory.
Salary is highly competitive and is commensurate with experience. The
University of Minnesota is an Equal Opportunity Employer.
For additional information or to make application contact:
Douglas H. Ohlendorf Phone:
Dept. of Biochemistry, Molecular Biology & Biophysics
Twin Cities Campus, University of Minnesota
ohlen at umn.edu
Lab web site: