PhD in Plant Virology
School of Biological Sciences, University of Bristol
PhD in Plant Virology
Investigating genes involved in symptom induction and the use of cross
protection for the control of Pepino mosaic virus in tomato
University of Bristol Supervisor: Professor Gary Foster
CSL supervisors: Dr Neil Boonham & Dr Nicola Spence
To investigate the genetic basis of the symptom differences observed
between Peruvian and European isolates of Pepino mosaic virus and to
investigate the potential use and mechanism of action of mild strain
inoculation (cross protection) to control the damaging effects of infection
by Pepino mosaic virus. This will be achieved using full length sequences
for both viruses, which will help generate infectious clones to be used in
gene exchange experiments and point mutation analysis to further
investigate the determinants of symptom production. This will help develop
cross protection experiments which will help to evaluate this as a strategy
for control of this damaging virus.
This studentship is ideal for any undergraduates with an interest in
virology, molecular biology and/or plant pathology. The studentship will
offer training in most modern molecular techniques, including PCR,
sequencing, use of microarrays, construction of infectious clones to
identify the genes involved in the interaction between Pepino mosaic virus
and the its host.
The Central Science Laboratory (CSL) is an Executive Agency of the
Department for Environment, Food and Rural Affairs (DEFRA). The project,
funded by CSL, includes consumables, tuition fees as well as maintenance of
£11,000 per annum. The studentship, available from 1 October 2004, will be
undertaken jointly between The University of Bristol and the Central
Science Laboratory in York.
Applicants should have or expect to obtain a good degree in
biology/biochemistry, molecular biology. Please send your CV to Prof. Gary
Foster in the first instance, along with the names/addresses/e.mails of two
referees. Deadline for applications is 25th March 2004. The position is
open to UK and EEC residents only.
Prof Gary Foster, School of Biological Sciences,
University of Bristol, Bristol BS8 1UG, United Kingdom.
E.mail : Gary.Foster at bristol.ac.uk
GD Foster, School Biological Sciences
Gary.Foster at bristol.ac.uk