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human papilloma virus (HPV)

Dr Nigel McMillan nmcmillan at gpo.pa.uq.edu.au
Tue Sep 10 09:39:10 EST 1996

stutjamalgeo at spock.colsf.edu wrote:
>    What is the new research on methods that may be used against this
> virus in humans?  Are acid applications just about the only methods used
> at this time?
                              Thanks for any responses...

Treatments for papillomavirus infections are fairly non-specfic and
destructive. The main problem is warts do not induce any inflamitory
response and therefor the immune system is fairly low key on getting rid
of it. Use of agents like liquid nitrogen to burn off warts is common.
Cytostatic (cell growth inhibitors) like polypoloidin (sp?) are also
used and Interferon alpha is licenced to treat genital warts.  New
techniques appear to revolve around inducing anitbody responses in the
form of a vaccine by inncoculating people with virus-like-particles (in
a manner similar to that used for hep B virus).  Othe companies appear
to be looking into expressing various other PV genes to induce other
types of responses.

Hope that helped

Nigel McMillan, PhD
Centre for Immunology and Cancer Research
University of Queensland

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