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HPV

Walter Hoeksma YD03 at MUSIC.FERRIS.EDU
Mon Jul 15 07:16:57 EST 1996


>
>> More than 70 genotypes of HPV have been identified of which about 20
>> infect the cervix. Of the HPV types that infect the cervix, types 16,
>> 18, 45 and 56 are considered high risk types.
>
>According to Fields Virology (3rd Edition 1996), the high risk types are:
>16, 18, 31, 45
>--
>Dr Alan J. Cann  PhD,   Department of Microbiology & Immunology,
>University of Leicester,  P.O. Box 138,  Medical Sciences Building,
>University Road, Leicester LE1 9HN,  UK.
>Email: nna at le.ac.uk     http://www-micro.msb.le.ac.uk/AJC/nna.html
>

According to Dr. B. Apgar, MD of the UNIVERSITY OF MICHIGAN MEDICAL
SCHOOL in a 1995 Hospital Practice article HPV types 6, 11,  42,  43
and 44 show no association with invasive cervical cancer and are thus
classified as low risk. Types 31, 33, 35, 51 and 52 are underrepresented
in cervical cancers and so are of of INTERMEDIATE risk. The high risk
types are 16, 18. 45 and 56.Type 16 is the most important viral subtype
of HPV because it is detected in 47.1% of invasive cancers and an equal
proportion of high grade squamous intraepithelial lesions.

Walt Hoeksema




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