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Ebola Virus Question

EdRegis edregis at aol.com
Tue Jan 2 01:44:30 EST 1996

>I am sure someone has thought of this before... but why couldn't 
>Ebola Reston be used as a vaccine for Ebola Zaire and Sudan? 

Probably because of the lack of homology and cross-reactivity among the
three.  Ebo-R was not fatal to humans although it was for cyno monkeys. 
Ebo-Zaire-Kikwit convalescent serum was used in the Kikwit outbreak when
Tamfum Muyembe injected 8 Ebola patients in Kikwit General Hospital with
serum taken from previous survivors of that outbreak, which had a 77%
fatality rate.  Seven of those eight survived, although some critics have
made the point that maybe those patients were getting better anyway.  

edregis at aol.com

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