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sterilization temperature

keith Appleyard k.appleyard at dundee.ac.uk
Mon Oct 16 07:56:10 EST 1995

soma at news.dorsai.org (*selah*) wrote:
>Would someone be able to say what the minimum temperature required is to 
>produce complete sterilization of all viruses?

Your question is incomplete since sterilization by this method is 
dependant not only on the temperature involved but also the duration of 
application, the initial viral load, presence of other materials, 
pressure etc

In general the higher the temperature the less time it has to be applied 
for.Boiling (100C) will do the job but will take some time to be 
completely effective, increase the pressure as in an autoclave and the 
temperature can be increased and the treatment time reduced to say 20 
minutes for a heavy viral load in the presence of significant amounts of 

Without further information about your requirement, conditions etc no one 
would be able to offer you a safe minimum which would apply at all times 
to all viruses!

Any lethal temperature applied for long enough will eventually kill all 
viruses. An idea would be that 100C would be the minimum since boiling is 
highly reproducible (at most altitudes). The length of time that you 
would have to apply this though is another matter.

Keith Appleyard BSc, Senior Scientific Officer, Virology
Ninewells Hospital and Medical School, Dundee DD1 9SY,
U.K, e-mail k.appleyard at dundee.ac.uk
Tel: U.K 01382 632559 Fax: U.K 01382 641907

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