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attnuatated influenza vaccine

Yoichiro Kino DG4Y-KN at ASAHI-NET.OR.JP
Thu Oct 12 18:48:33 EST 1995


At  9:22 PM 95.10.11 -0400, smt3 at lehigh.edu wrote:
>I'm looking for information on attenuated flu vaccines.  Has anyone heard of
>any studies that have been done recently?  Also, does anyone know if the FDA
>has anything to say on the subject of live virus vaccines?  I would appreciate
>any help or comments.
>  

Although several attenuated live influenza vaccines have been evaluated so
far, only vaccine survived is cold-adapted live influenza vaccine
originally developed by Dr. H.F. Maassab at The University of Michigan. 
Dr. Peter Wright, Vanderbilt University, summarized recent clinical data at
a meeting " Vaccine, One Hundred Years After Louis Pasteur " held at
Institut Pasteur, Paris from September 24-28, 1995.  You can find one of
recent publication in JID 172:1-10.  General infromation is in " Vaccine,
2nd edtion " edited by Drs. Plotkin and Mortimer, W. B. Saunders Company,
Philadelphia. 

Wyeth-Lederlee has already withdrawn from the clinical development.  At
present Aviron, San Francisco based bioventure, is involved in the program.
 

I hope this is of any help.

Yoichiro Kino, Ph.D.$B!!(B($B>kLnMN0lO:(B)
The Chemo-Sero-Therapeutic Research Institute$B!!(B( ($B:b(B)$B2=3X5Z7l at 6NEK!8&5f=j(B)
664 Okubo, Shimizu, Kumamoto 860, Japan ($B7'K\;T at 6?eD.Bg7&(B668)

Phone: (81)-968-37-33100, ex.268 
Fax: (81)-968-37-3616




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