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HIV reversal?

Ian A. York york at mbcrr.dfci.harvard.edu
Thu Mar 30 08:36:40 EST 1995

In article <kiltyD694KA.9qp at netcom.com> kilty at netcom.com (Kathleen Richards) writes:
>The news is reporting a child born of a mother dying of AIDS,
>born HIV positive but now showing clear of the virus some 5
>years later.  It was spoken of as "the first documented case of
>a human being clearing itself of the viral infection of HIV".

	I just saw that article, in the New England Journal of Medicine.  
It looks moderately convincing.  The child is now 5 yr old, and no HIV 
has been detected for several years.  The child was apparently infected 
at birth, and there were a couple of positive cultures and positive PCR 
tests in the first year, pulling out the same HIV isolate.  The long 
interval of HIV -ve status suggests that the child really is free, 
although they note that they can't be sure that there isn't some virus 
hiding out in lymph nodes etc.  The biggest question seems to be whether 
the child was really infected originally, and the multiple isolations of 
the same variant suggest that that was real, although again we can't rule 
out a weird repeated contamination or something like that - it seems 
unlikely, though.
	There was nothing particularly unusual noted about the child, so 
they have no suggestions as to how the virus was cleared.


Ian York   (york at mbcrr.harvard.edu)
Dana-Farber Cancer Institute, 44 Binney St., Boston MA 02115
Phone (617)-632-3921     Fax  (617)-632-2627

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