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particle to pfu ratios

Bill Demers demers at cts.com
Tue Jul 25 01:04:36 EST 1995


Suppose a purified virus prep has a particle number:pfu ratio of 50:1.

Does this mean that 49 out of 50 particles are non-infectious and most of
the prep is "junk"
or
that pfu is a concentration of virus required to detect a single
infectious event, ie. 50 infectious particles exposed to cells has the
chance of forming a single plaque.



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