Jean-Paul cadoret (jpcadore at ifremer.fr) wrote:
: Hi netters
: The sv40 doesn't repilcates only in monkey, right ?
: have the factors responsible for this specificity identified ?
: have they been cloned. Is the primase the only one ?
There are two human viruses that are very, very close in sequence, if not
identical to SV40. One is called JK virus I think (JC?), the other's name
escapes me. One infects the kidney, the other infects the brain. Sorry I
couldn't be more certain. Maybe someone else here knows.
Then there was also that incident where thousands of people were
accidentally infected with SV40 that was a contaminant in monkey
kidney-prepared vaccine. So it can infect humans.
As far as factors being cloned, the whole virus is less than 10kb and the
whole thing has been cloned.
--
Jim Gibbs gibbs at fas.harvard.edu
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