That seems like a pretty high dilution to me. Are you sure your decimal
points are all in the right place? I remember somewhere in the depths
of my memory that 10^17 poliovirus particles will fill a ping pong ball.
So I don't think 10^23 virus particles can be suspended in 1 ml of
cell culture medium. I understand the difference between TCID50 and
absolute particle numbers, I'm just thinking intuitively.
krjk1 at stirling.ac.uk (Mr K R John Kollanoor) wrote:
>> Is there a theoratical maximum for the number of virus progeny a cell
> culture supernatant can have?
> Is there any possibility of a titer of 10^-23(TCID50/ml) in any of the virus
> infected cell culture supernatant ?
> I would appreciate if someone could answer these questions.