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Prions

Bruce Phillips bap at MED.PITT.EDU
Tue Apr 25 10:30:38 EST 1995


	In answer to a recent query, the article about prion-diseases bewing
caused by a Spiroplasma bacterium was written by Frank O. Bastian and was
published in the ASM News, vol 59 #5 in 1993.  Apparently, these bacteria
are very small, passing thru pores of 50 nm (?), are neurotropic and very
fastidious in their nutrition, and proteins extracted from them form 
fibrils similar to scrapie-associated fibrils characteristic of many prion
disease processes.  According to Bastian, as I understand it, antibodies 
formed in scrapie-infected animals reacts to these bacteria.



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