FW: DNA Repair Interest Group - UPDATE - February 26, 2004

Charles Miller rellim at tulane.edu
Mon Mar 1 15:52:30 EST 2004

------ Forwarded Message
From: "Kenneth H. Kraemer" <khk at nih.gov>
Reply-To: Ken Kraemer <kraemerk at nih.gov>
Date: Thu, 26 Feb 2004 18:52:22 -0500
Subject: DNA Repair Interest Group - UPDATE - February 26, 2004

DNA Repair Interest Group - UPDATE - February 26, 2004

1.      VIDEOCONFERENCE - Mar 16, 2004 - Tues 12:30 PM - Dr. Alan Lehmann
- Brighton, UK - Translesion Synthesis and Polymerase Switching in Human
2.      NIH SEMINARS OF NOTE: March 10, 2004 -10:00 AM - Dr Sephen Meyn,
First Aid for Broken DNA: The Role of ATM and TRF2 in the Initial Response
to DNA Breaks
3.      CONFERENCES -  Unstable Microsatellites and Human Disease -Feb
28-March 4, 2004 Banff, Canada;  DNA Repair Workshop - Smolenice, Slovakia
- MAY 2-5, 2004;  Midwest DNA Repair Symposium, June 5-6, 2004, Lexington,
KY;  International Congress of Photobiology June 10-15, 2004, Korea;
International Conference -chemical & biological problems of Proteomics
(cbpp-2004) Novosibirsk, Russia, July 5-9, 2004; Methods in Protein
Structure Analysis Conference for 2004 (MPSA2004),University of
Washington, Seattle, August 29 -September 2, 2004; DNA Repair and
Mutagenesis: from Molecular Structure to Biological Consequences, Bermuda
Nov 14, 2004
TX; Lyon, France; Harwell, UK; College Park, MD; Research Triangle Park,
NC; Livermore, CA;  Boston, MA; New York, NY
6.      Electronic Contacts

I was recently informed by Dr. Samuel Bennett (
bennetsa at onid.oregonstate.edu ):
"Dr. Dale Mosbaugh died suddenly of a heart attack February 17, 2004. He
is survived by his wife Kathy and two children, Christine and Brian. A
Celebration of the Life of Dale Mosbaugh memorial service is planned for
Sunday, February 29, 1-4 pm, Corvallis, Oregon, at a local high school
gymnasium where Dale was very active as a wrestling coach."

Mar 16, 2004 - Tues 12:30 PM - Dr. Alan Lehmann - Brighton, UK -
Translesion Synthesis and Polymerase Switching in Human Cells

(origin); Room 1E03 GRC Baltimore, MD; Lawrence Livermore Labs, Livermore,
CA Univ of Michigan, Ann Arbor; University of Pittsburgh; MD Anderson,
Smithville, TX; Building 101 Room B200, NIEHS, Research Triangle Park, NC;
State University of New York, Stony Brook, NY; Univ of Kentucky,
Lexington, KY; Building 549, Conference Room A,  FCRDC, Frederick, MD;
Brookhaven National Labs, Upton, NY; Oregon Health & Science University,
Portland, OR  and live on the internet at http://videocast.nih.gov

[Note: A larger and more up to date list of future and past
videoconferences can be found on the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]


April 20, 2004 - Tues 12:30 PM - Dr. David Wilson - NIA, NIH - Regulation
of Central Steps in Human Base Excision Repair

May 18, 2004 - Tues 12:30 PM -  Dr. Larry Thompson - Lawrence Livermore
National Lab, Livermore, CA - History of DNA Repair: Chinese Hamster Cells
and DNA Repair - A Long-Lasting Affair

June 15, 2004 - Tues 12:30 PM - Young investigator showcase:  Dr.
Francesca Storici - NIEHS - Addressing Mechanisms of Recombination and
Double Strand Break Repair in Yeast with Targeted Oligonucleotides and the
Delitto Perfetto Approach; Dr. Diane Cabelof - Wayne State, Detroit -
Induction of Spontaneous Tumors in beta-pol Haploinsufficient Mice; Dr.
Sikandar Khan - NCI - Two essential splice lariat branchpoint sequences in
one intron in a xeroderma pigmentosum DNA repair gene

To date 67 of these videoconferences have been archived and are available
for viewing at your leisure on the internet. You will need a web browser
(with a high speed link) and free Real Video software.  Setup details and
access are available at the NIH videocast website:
http://videocast.nih.gov. Go to Past events; DNA Repair Interest Group

Note: Technical improvements are made regularly on this site to increase
transmission speeds and ease of access. If you were not successful in
viewing these videos in the past it is worth trying again.   We just
received a log of the use of these videocasts. They were downloaded nearly
10,000 times in the past two years!

Feb 17, 2004 - Dr. Dmitry Gordenin - NIEHS- Inhibition of Mismatch Repair
by Cadmium [Note: An Adobe Acrobat file with slides from this talk can
also be downloaded at this site.]

Jan 20, 2004  - Dr. Steve Kowalczykowski - Biochemistry of Recombinational
DNA Repair: Common Themes

Dec 16, 2003 - Tues 12:30 PM - Dr. Andre Nussenzweig - Experimental
Immunology Branch, CCR, NCI, NIH -The Role of DNA Breaks in Genomic

Nov 18, 2003 - Tues 12:30 PM - Dr. Lei Li - Univ of Texas, M.D. Anderson
Cancer Center - DNA Damage Cell Cycle Checkpoint: Beyond Buying Time for

Oct 14, 2003-  Dr. Alain Sarasin, Institut Gustave Roussy, Villejuif
France - Xeroderma pigmentosum : Role of the XP variant pol eta gene in
UV-induced mutagenesis.  Toward a gene therapy in XPC patients?

Sept 16, 2003 - Dr. Satya Prakash - Univ of Texas, Galveston -Translesion
synthesis DNA polymerases of yeast and humans

Sept 16, 2003 - Dr. Satya Prakash -Studies of human DNA repair diseases in

June 17, 2003 - Dr. John Bradsher, NCI, NIH, Roles of the CS proteins in
Nucleotide Excision Repair and Transcription;

June 17, 2003 - Dr. Tom Rosenquist, SUNY, NEIL proteins and base excision
repair in mice

June 17, 2003 -  Dr. Karen Vasquez, Smithville, TX - Processing of
site-specific DNA lesions by DNA repair and recombination pathways [Note:
The posting of this talk will be delayed at the request of the speaker.]

May 20, 2003 -  Dr. Errol Friedberg, Univ of Texas Southwestern, Dallas,
Tx - Honest Jim Revealed- The Writings of James D. Watson

Apr 15, 2003 - Dr. Qingyi Wei, M.D. Anderson, Houston, Tx - DNA Repair
Function, Polymorphisms and Cancer Risk in the General Population

Mar 11, 2003 - Dr. Sankar Mitra, Univ of Texas, Galveston - Oxidative
Damage Repair and Its Co-ordination in the Mammalian Genome.[Note: The
posting of this talk will be delayed at the request of the speaker.]

March 05, 2003  - Dr. Stephen J. Elledge - Baylor College of Medicine
Houston, TX  - Sensing and Responding to DNA Damage  [Note: this talk was
part of the NIH Wed afternoon lecture series and was sponsored by: the
Mouse Club and Washington Area Yeast Club Interest Group and is now posted
on the DNA Repair Interest Group part of the videocast.nih.gov website.]

Jan 21, 2003 - Tues 12:30PM - Dr. Jack Taylor, NIEHS - Epidemiologic
studies of DNA repair gene polymorphisms and cancer risk

Dec 17, 2002 - Dr. John Tainer, UC Berkeley - Conformational Controls and
DNA Repair Coordination - NEWLY POSTED

Through the miracle of videotape we now have been able to post most of the
DNA Repair Interest Group videoconferences from 1998,1999, 2000, 2001 and
2002 on the web site.  These include talks by Drs. Anderson, Beernik,
Bogenhagen, Bohr, Brash, Brooks, Brosh, Chu, Cleaver, Chen, Copeland,
Drotschmann, Emmert, Essigman, Fornace, George, Glazer, Grossman,
Hanawalt, Jin, Kashlev, Kraemer, Kunkel, Leadon, Liu, Ljungman, Marini,
Matson, Matsumoto,  McKay, Pommier, Ramsden, Setlow, Schofield, Sharan,
Sobol, States, Stefanini, Sung, Sutherland, Tomkinson, Thompson, Wang,
Wood, Woodgate, Yanamadala, and Yarosh.

March 10, 2004 - Wed 10:00 AM Building 5 Room 127 Dr Sephen Meyn, Univ of
Toronto - First Aid for Broken DNA: The Role of ATM and TRF2 in the
Initial Response to DNA Breaks - Information: R. Daniel Camerini-Otero

3.    CONFERENCES -  Unstable Microsatellites and Human Disease -Feb
28-March 4, 2004 Banff, Canada;  DNA Repair Workshop - Smolenice, Slovakia
- MAY 2-5, 2004;  Midwest DNA Repair Symposium, June 5-6, 2004, Lexington,
KY;  International Congress of Photobiology June 10-15, 2004, Korea;
International Conference -chemical & biological problems of Proteomics
(cbpp-2004) Novosibirsk, Russia, July 5-9, 2004; Methods in Protein
Structure Analysis Conference for 2004 (MPSA2004),University of
Washington, Seattle, August 29 -September 2, 2004; DNA Repair and
Mutagenesis: from Molecular Structure to Biological Consequences, Bermuda
Nov 14, 2004
[Note: A larger and more up-to-date list of conferences can be found on
the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]


The 4th International Conference on Unstable Microsatellites and Human
Disease will occur in 2004 on February 28-March 4 at the Banff Center in
the Rocky Mountains of Canada (ski season in ski heaven).  This meeting
has occurred about every two years since 1997.  The meeting will continue
to focus upon the most recent advances in understanding repeat instability
of nucleic acids and proteins and their relationship to human diseases,
inherited and other.  Since 1991, when this type of mutation was first
associated with disease there have been at least 36 different hereditary
diseases found to be caused by this form of mutation as well as numerous
diseases that are associated with genetic instabilities.  Diseases
including Huntingtons disease, myotonic dystrophy, fragile X mental
retardation and cancer-associated repeat instabilities will be

The multi-disciplinary nature of the research field requires the gathering
of clinicians, diagnosticians, pathologists, geneticists and molecular
biologists.  In addition to focussing upon the most recent scientific
advances, the goals of the meeting include 1) enhancing the exchange of
information and 2) to stimulate the initiation of collaborative research.
This meeting has a proven track record of rapidly sharing new information,
stimulating scientific exchange, forming collaborations and has served as
an excellent venue for training of young scientists (graduate students,
post-doctoral fellows and PIs).  This is the premier meeting on these
mutations and diseases.

In addition to invited speakers, a portion of platform presentations will
be selected from submitted abstracts (preferably from graduate students
and post-doctoral fellows).

Banff is a great place to think big about science.  The meeting venue is
set in the heart of the scenic Canadian Rocky Mountains, Banff which has
spectacular views, amazing skiing, hiking, skating, hot springs, and other
activities that the attendees can participate in during non-meeting hours
to form lasting interactions.

More information may be found therein   http://www.microsatellites.ca
We are planning an exciting, educational, stimulating scientific meeting.
If there are any questions that I may answer, please feel free to contact
me at any time.

Christopher E. Pearson, Ph.D.

tel:  (416) 813-8256 (office)
fax:  (416) 813-4931 (office)
email: cepearson at genet.sickkids.on.ca


The Cancer Research Institute, Slovak Academy of Sciences organizes the
4th DNA Repair Workshop in Smolenice Castle, Slovakia, May 2-5, 2004. It
will be a small meeting for about 60- 80 participants (maximum capacity of
the castle).

The second announcement with the Main topics,Preliminary program,
Registration, Accomodation and Abstract forms, deadlines and additional
informations is available on the following web-site:

We are looking forward to meet you in Smolenice.

Best regards
Miroslav Pirsel
Organizing Committee

Miroslav Pirsel
Cancer Research Institute
Slovak Academy of Sciences
Vlarska 7
833 91 Bratislava 37
Slovak Republic
Phone : 00421-2-59327 303
Fax : 00421-2-59327 350
e-mail: miroslav.pirsel at savba.sk

3.3 The 6th Annual Midwest DNA Repair Symposium, June 5-6, 2004,
Lexington, KY

Dear Colleagues,
We will be holding The 6th Annual Midwest DNA Repair Symposium in
Lexington, KY from June 5-6 (Sat.-Sun.), 2004. Rick Wood has agreed to be
one of our keynote speakers. As in the past, most speakers/poster
presentations will be selected from submitted abstracts. Please consider
joining us. A website providing more detailed information will be created
in the future. The local organizing committee also includes Guo-Min Li,
Zhigang Wang, David Orren, Liya Gu, Andy Pierce, and Isaac Wong. We hope
that you will circulate this among your colleagues and consider joining us
next June.

Best Regards, Isabel Mellon

10-15, 2004.

The 14th International Congress on Photobiology sponsored by the
International Union of Photobiology and hosted by the Korean Society of
Photoscience, Photobiology Association of Japan, and Asia and Oceania
Society for Photobiology will be held June 10-15, 2004, on the island of
Jeju, Korea. Both Korean Society of Photoscience, Korean Photodynamic
Association, and Asia and Oceania Society for Photobiology will also hold
their annual meetings in conjunction with the Congress at the same time.
More details can be found at:

I would like to invite you to register to participate in the Congress by
visiting the website and filling out the registration form therein. To
make the Congress successful, your suggestions and contributions are
essential and will be greatly appreciated by the Organizing Committee. In
order to make the Congress scientifically attractive, we plan to organize
nearly 50 symposia and 10 special lectures. In addition, we are planning
to present a national photobiology-society sponsored Plenary Lecture each
day of the

The Congress venue is the Island of Jeju. It is one of the most beautiful
islands in the world. It offers many sightseeing and leisure attractions.
Bring your family and friends. You will enjoy it.

See you all here in Jeju, Korea, in Year 2004!
Best wishes,
Pill-Soon Song
Congress President-ICP2004


On behalf of Organizing Committee we are pleased to inform you that an
international Conference on Chemical & Biological Problems of Proteomics
will be held in Novosibirsk, Russia, from 5th to 9th of July, 2004. The
scientific program of the Conference will include plenary lectures, short
talks and poster sessions.

The main topics include:

Functional and Structural Proteomics:
- DNA repair
- replication
- translation
- transcription

Clinical Proteomics:
- cancer
- immune diseases
- hereditary diseases
- infectious diseases

If you or your colleagues find it interesting, please visit the
Conference web page at http://www.niboch.nsc.ru/annonc.htm for
more information. The registration deadline is March 1st.

Organizing Committee:
Olga Fedorova (chairperson)
Vladimir Richter (vice-chairperson)

Scientific Committee:
Valentin Vlassov (chairperson)
Renad Sagdeev (vice-chairperson)
Dmitry Knorre
Galina Karpova
Olga Lavrik
Georgy Nevinsky
Georgy Georgiev
Sergey Inge-Vechtomov
Anatoly Miroshnikov
Alexander Gabibov
Sergey KochetkovContact information:
Dmitry Zharkov, PhD
Laboratory of Repair Enzymes
Institute of Chemical Biology and Medical Research
Novosibirsk, Russia 630090
E-mail Address:  dzharkov at niboch.nsc.ru
Conference web page: http://www.niboch.nsc.ru/annonc.htm

(MPSA2004),UNIVERSITY OF WASHINGTON, SEATTLE,  August 29 -September 2,

Scientific Program
Keynote Speaker: Stan Fields, Howard Hughes Medical Institute,
University of Washington, Seattle, USA (confirmed)
Scientific Sessions and Invited Speakers
I. The Interactome
Michael Snyder, Yale University, USA (confirmed)
II. Analytical Strategies in Proteomics
Ulf Landegren, Uppsala University, Sweden (confirmed)
Barry L. Karger, Northeastern University, USA (confirmed)
Dick Smith, Pacific Northwest National Lab, USA (confirmed)
III. Computational Biology and Protein Families
David Eisenberg , UCLA, USA (confirmed)
Anna Tramontano, University of Rome "La Sapienza", Italy
David Baker, University of Washington, Seattle, USA (confirmed)
Keith Dunker, Indiana University School of Medicine, USA
IV. Protein Posttranslational Modifications and Cell Signaling
Steven A. Carr, Millennium Pharmaceuticals, USA (confirmed)
Jeffrey J. Gorman, Institute For Molecular Bioscience, The
University of Queensland, Australia (confirmed)
Gerald W. Hart, Johns Hopkins University Medical School (confirmed)
V. High Throughput Technologies for Cloning, Protein Production and
Frank R. Collart, Argonne National Laboratory, USA (confirmed)
Mark T. Fisher, University of Kansas Medical Center, USA
VI. Protein-Protein Interactions and Analysis of Macromolecular
Jill Trewhella, Los Alamos National Laboratory, USA
Min Li, Johns Hopkins University School of Medicine, USA
Jeff Ranish, Institute for Systems Biology, USAVII. Chemical Proteomics
and Imaging Methods
Ben Cravatt, Scripps Institute, USA
Mark Ellisman, Center for Research in Biological Structure, UCSD
VIII. Protein Engineering and Biotechnology
John R. Desjarlais, Director, Protein Engineering, Xencor,
Monrovia, CA, USA
IX. Cell Pathways Regulation and Metabonomics
Roger Brent, The Molecular Sciences Institute, USA
Jeremy Nicholson, Imperial College, London, England
X. Systems Biology
Lee Hood, Institute for Systems Biology, USA
Trey Ideker, University of California, San Diego, USA

Website: http://depts.washington.edu/biowww/mpsa2004
For more information, please contact: mpsa2004 at u.washington.edu


General Information
The 34th Annual Meeting of the EEMS will be held from 4 to 8 September
2004 in Maastricht, the Netherland's southernmost city, with a charming,
international character.

The central theme of the meeting will be "Genes and the environment.
Bridging the gap", referring to the current exciting developments in
application of the latest technologies in genetic toxicology and
carcinogenesis, but also to the bridges spanning the river "Maas" that
floats through Maastricht. During the congress special attention will be
paid to the influence of new technologies (toxicogenomics, proteomics,
etc.) on R&D and on regulatory requirements.

The meeting is organised in plenary symposia with invited speakers in the
morning, and two parallel workshops in the afternoon with presentations
selected from submitted abstracts. In addition to that, poster
presentation will be organised in two sessions.

"       DNA damage, repair and cell cycle control
"       Toxicogenomics: new tools in genetic toxicology
"       Genomic stability and aging
"       Influence of genetic variation on cancer
"       Natural mutagens and carcinogens

"       Nutrigenomics for healthy and safe foods
"       DNA damage, repair and cell cycle control
"       Influence of genetic variation on cancer
"       Oxidative damage
"       Biological clocks, chronotoxicology and therapy
"       Hazard identification by omics technologies
"       Health risk assessment; guidelines, harmonisation, validation,
"       Genomic stability and aging

 The Meeting is at Crown Plaza, a major Congress Centre and Hotel, located
in the old centre of Maastricht.


Local organising committee
Joost van Delft (President, University of Maastricht),Jan van Benthem
(vice-President), Peter Weterings (Treasurer), Bert van der Horst, Bert
van Zeeland, Cyrille Krul, Els van Vliet, Frederik-Jan van Schooten,
Frederique van Acker, Gerrit Alink, Harry van Steeg, Harry Vrieling, Ineke
Verspeek, Jos Kleinjans, Madeleine Nivard, Rob Baan


Dear Colleagues,
We are writing to let you know that we will be organizing an ASM
Conference entitled "DNA Repair and Mutagenesis: From Molecular Structure
to Biological Consequences" sponsored by the American Society for
Microbiology to be held at the Fairmont Southampton Princess, Bermuda, NOV
14-20, 2004. The conference will bring together the various subdisciplines
that collectively comprise the field of DNA Repair and Mutagenesis.
Meetings of this type have been held at approximately four year intervals
since 1974, the preceding one in this informal series having been at
Hilton Head, South Carolina in 1999, and have played a critical role in
the development of this exciting area of research.

Speakers will include: Genevive Almouzni, Lorena Beese, Serge Boiteux,
Jaap Brouwer, Keith Caldecott, Judith Campisi, Gilbert Chu, Priscilla
Cooper, Titia de Lange, John Diffley, Sylvie Doubli, Jean-Marc Egly,
Stephen Elledge, Tom Ellenberger, Rick Fishel, Marco Foiani, Errol
Friedberg, Robert Fuchs, James Haber, Fumio Hanaoka, Phil Hanawalt, Jan
Hoeijmakers, Peggy Hsieh, Ian Hickson, Stephen Jackson, Maria Jasin, Penny
Jeggo, Joe Jiricny, Roland Kanaar, Richard Kolodner, Stephen
Kowalczykowski, Thomas Kunkel, Tony Leadon, Alan Lehmann, Tomas Lindahl,
Bndicte Michel, Sankar Mitra, Paul Modrich, Leon Mullenders, Tanya Paull,
John Petrini, Louise Prakash, Miroslav Radman, Rodney Rothstein, Leona
Samson, Alain Sarasin, Erling Seeberg, Jesper Svejstrup, John Tainer,
Shunichi Takeda, Kiyoji Tanaka, Graham Walker, Susan Wallace, Stephen
West, Sam Wilson, Richard Wood, Roger Woodgate, and Wei Yang.

Some additional speakers on timely topics will be invited closer to the
date of the meeting, and furthermore, speakers will be chosen from among
the submitted abstracts for shorter presentations.

Careful thought has been given to the choice of the site and the design of
the program so that participants will be able to enjoy the type of
opportunities for informal discussions and interactions that are normally
found only at smaller meetings. A special feature of the meeting will be
travel grants to help support the participation of graduate students and
postdoctoral fellows. Additional information concerning the meeting and
the program is available at:
We hope you will mark these dates on your calendars. We look forward to
seeing you in Bermuda in December 2003!

Best Wishes
Graham Walker, Susan Wallace, and Priscilla Cooper

TX; Lyon, France; Harwell, UK; College Park, MD; Research Triangle Park,
NC; Livermore, CA;  Boston, MA; New York, NY  [Note: Check the list for
more Job Opportunities on the DNA Repair Interest Group web site:
http://www.nih.gov:80/sigs/dna-rep/ ]

We are studying molecular, cellular and clinical abnormalities in patients
with defective DNA repair and possible links of these genes to disease in
the general population. Current emphasis is on xeroderma pigmentosum,
Cockayne syndrome and trichothiodystrophy.  A postdoctoral position is
available for a talented individual (M.D., Ph.D. or MD-PhD) with less than
5 years of postdoctoral experience who has knowledge of molecular biology
and DNA repair.

To apply, send CV and bibliography and names (with contact information) of
3 references to:

Kenneth H. Kraemer, M.D.
Basic Research Laboratory
National Cancer Institute, NIH
Building 37 Room 3E24
Bethesda,  MD 20892
TEL: 301-496-9033    FAX: 301-496-8419
e-mail: kraemerk at nih.gov

NIH is an equal opportunity employer.

A postdoc position in computational biology is available at the UTMB in
motif analysis and identification in DNA repair proteins. Experience in
programming (C, PERL), database construction (MySQL), sequence analysis,
molecular dynamics simulations and docking, NMR and protein structure
analysis would all be helpful for the project.

Please send CV, copies of publications and references to:
Prof. Werner Braun,
Department of Human Biological Chemistry and Genetics,
Sealy Center for Structural Biology,
Galveston TX 77555-0857,
fax: 409-747 6000, tel. 409-747 6810,
werner at newton.utmb.edu.


A post-doctoral position is available immediately at the Genome Analysis
(GAN) Group of IARC, based in Lyon, France. The selected person will be in
charge of projects aimed at studying genetic polymorphisms of a battery of
genes involved in DNA repair
and xenobiotic metabolism as cancer risk factors. In particular, the
fellow will work on a project recently funded by NCI which will measure
the contribution of SNPs of 53 genes which are potentially involved in the
susceptibility of cancers of the lung and upper aerodigestive tract using
a large sample size of 10,000 subjects

We have state-of-the-art genotyping technology (currently based on TaqMan
and DNA microarrays) and an exciting multidisciplinary, multicultural and
international working environment. We offer tax-free salaries
(approximately 25,000 euros/year).

The ability of speaking, reading and writing in English is a requirement.
Knowledge of French is desirable but not necessary. Background in genetics
and/or epidemiology is required. Experience in genotyping projects,
association studies and/or biostatistics is an asset.

If you think you are the person we are looking for, please send a complete
CV in English, including list of publications and names of two referees
to:Federico Canzian, Ph.D.
Genome Analysis Group
International Agency for Research on Cancer
150, cours Albert-Thomas, F-69372 Lyon, France
Tel. +33-4-72738698
Fax +33-4-72738388
E-mail canzian at iarc.fr



A post-doctoral position is available immediately to study bacterial DNA
recombination enzymes. One project is structure-function studies on the E.
coli RecBCD enzyme. Immediate research goals are to identify and
investigate DNA-binding and metal-ion binding sites in RecBCD enzyme that
are relevant for Chi-sequence-dependent regulation of RecBCD. A second
project involves biochemical and biological study of the RecD-homologue
protein from the bacterium Deinococcus radiodurans. Further information
about our research and a list of recent relevant publications is available
at www.chem.umd.edu/faculty/biochem/julin/julin.htm

Applicants should have a Ph.D. in biochemistry, molecular biology, or
related field. Previous experience with enzymology, protein chemistry,
and/or recombinant DNA techniques is desirable.

To apply, send a CV, a summary of research interests and skills, and the
names, addresses, and email addresses of three references to:

Prof. Douglas Julin, Postdoctoral Research Associate Search
Department of Chemistry & Biochemistry
University of Maryland, College Park MD 20742
email dj13 at umail.umd.edu
FAX: 301-314-9121

NIH POSTDOCTORAL POSITION to investigate highly relevant genome stability
issues using yeast and/or human cell systems.  Research projects are
available in several related directions that include i) DNA double-strand
breaks (origin, repair, recombination, replication, cell signaling, and
real time analysis); ii) replication and mutation avoidance; iii)
influence of mitochondria on genome stability; and iv) human p53 function,
role in genome stability and model for evolution of regulatory networks
(see http://dir.niehs.nih.gov/dirlmg/home.htm).  A variety of genetic,
molecular, and functional genomics approaches are used that have been
developed in this Section. Along with exceptional facilities and
resources, the Section provides a highly interactive and unique scientific
environment with several areas of expertise, so as to create an
exceptional training opportunity.
The Section is part of the Laboratory of Molecular Genetics (LMG) with
many PI's renowned for their contributions to the area of genome stability
and is located at the National Institute for Environmental Health Sciences
(NIEHS) of the NIH.  NIEHS is in a highly attractive area of North
Carolina that is central to prominent research institutions.  A unique
feature of the postdoctoral program is the opportunity to apply for
special grants for subsequent tenure-track academic appointments. Salary
and benefits are competitive.
Application.  Send CV & names of references to Dr. Michael Resnick, Head,
Chromosome Stability Section, NIEHS, P.O. Pox 12233, Research Triangle
Park, NC  27709; resnick at niehs.nih.gov

A California Breast Cancer Research Program-funded postdoctoral fellowship
is available to study the role of DNA oxidation in breast tumor
progression. In particular, the laboratory is interested in assaying for
the in vivo oxidation products of 7,8-dihydro-8-oxo-2'-deoxyguanine, a
known DNA damage product in breast cells. The hypothesis is that these
products play a role in tumor initiation and progression towards
malignancy. Experience in molecular and cell biology using radiolabeled
probes is desired. Salary: $40,000-55,000. Please send resume to: Dr. Paul
Henderson, L-441, Biology and Biotechnology Research Program, Lawrence
Livermore National Laboratory, Livermore, CA 94551. e-mail:
henderson48 at llnl.gov


Postdoctoral position - Biological Engineering Division, Massachusetts
Institute of Technology, Cambridge, MA. A postdoctoral position is
available in the laboratory of Bevin P. Engelward to develop novel
transgenic mouse systems for measuring mitotic homologous recombination
via fluorescence detection within tissues, and to study interactions
between DNA excision repair and homologous recombination in eukaryotes.
Experience in genetics, molecular biology, cell biology, DNA repair, or
knockout/transgenic mouse technology is desired. Interested individuals
should send their C.V., a description of their research experience and
interests, and the names of three references to:

Bevin P. Engelward, Sc.D.
Associate Professor of Biological Engineering
MIT Biological Engineering Division, 56-631
77 Massachusetts Avenue
Cambridge, MA 02139
MIT is an Equal Opportunity/Affirmative Action Employer

A postdoctoral position is available immediately at the Department of
Radiation Oncology, Center for Radiological Research, Columbia University
to pursue studies of signal transduction pathway(s) involved in radiation
induced DNA damage and bystander response in mammalian cells. Candidate
with a recent a Ph.D. degree in Biochemistry, Molecular biology or Cell
biology is required. Experience in cell culture, protein biochemistry and
signal transduction research experience is preferred.
Interested candidates can submit their resume, areas of research interests
and three letters of recommendations to either
Prof. Charles R. Geard or Dr. A.S. Balajee
Department of Radiation Oncology
Center for Radiological Research
College of Physicians and Surgeons
Columbia University, VC-11, Room 243
168th Street, 630 West
New York, NY 10032.
Informal enquiries can be made to Dr. A.S. Balajee (ab836 at columbia.edu).

[Note: There are more commercial reagent sources listed on the DNA Repair
interest group website: http://www.nih.gov:80/sigs/dna-rep/    These
sources are listed as a convenience to our readers and do not constitute
an endorsement of any of these companies or their products.]

        5.1 Biocompare - This website www.biocompare.com calls itself "The
Buyer's Guide for Life Scientists" This site includes comparisons of many
reagents that are useful for DNA repair studies including a listing of

        5.2 Genetex - Antibodies for DNA repair www.genetex.com Located in

        5.3 Phoenix BioTechnologies Inc. - Provider of DNA to labs with
specialized requirements, Phoenix BioTechnologies announces the
availability of DNA synthesis services for oligonucleotides containing
cyclobutane T-T dimers. Working with Glen Research, we have optimized
synthesis with this amidite to attain excellent coupling efficiencies and
high product yields. Synthesis services are currently available at the 1
umol scale.

For additional information, please contact us at your convenience through
the information listed below.
Donna Brown
Company Scientist
Phoenix BioTechnologies, Inc.
1000 Meridian Street
Huntsville, AL 35801
Toll-free 866-319-0900
FAX 256-319-0902
dbrown at phxbio.com

        5.4 Abcam Ltd ( www.abcam.com ) - At present, we have a fairly
substantial range of products including those relating to DNA damage and
repair (246 in total), and are actively developing this as we speak.

Please find a hyperlink provided below for your review.


Thank you in advance for your time and kind consideration.

Miss Lesa Rodgers
Marketing Assistant
Abcam Ltd
21 Cambridge Science Park
Milton Road, Cambridge,
Cambridgeshire CB4 0TP
United Kingdom

        5.5 Bethyl Laboratories, Inc. - Antibodies for DNA Damage/Repair
and related research (www.bethyl.com)  New antibodies include SDS3, DMAP1,
KIF14, DIS, MCM2, MCM3, MCM4, MCM6, MCM7, MCM10, Claspin, BRD2, Pumilio 1,
Pescadillo, Mre11, NBS1, SERCA2, AMPK and RFC1. http://www.bethyl.com

        5.6  Reliable Biopharmaceutical Corporation - As the leading U.S.
manufacturer of modified nucleic acids, we wanted to introduce you to our
newest product: cis-syn TpT Cyclobutane Dimer Phosporamidite. Specially
developed for the DNA repair and research markets. You can see our
homepage and our TpT Dimer Amidite webpage to better understand our
company and products.

If I or my staff can answer any of your specific questions, please call at
your convenience.

Sourena Nadji, Ph.D.
Reliable Biopharmaceutical Corporation
Director of Research and Development

        5.7 Novus Biologicals, Inc., Littleton, CO - Antibodies for DNA
Repair Research (http://www.novus-biologicals.com/research.php/8) and
other research applications (www.novusbio.com). New antibodies include
hTERT, NTH, 53BP1, ATM Kinase (ser 1981), ATR, MCM8, MSH6, Raptor, Rpb2,
pol Beta, GPX-6, SUG1, Rad1, and BACH1. For more information
Bryan Tinsley
Novus Biologicals, Inc.
5951 S. Middlefield Rd. Suite 103
Littleton, CO 80123
fax: 303-730-1966
bryan at novusbio.com

        5.8 Santa Cruz Biotechnology, Inc, Santa Cruz, CA - Antibodies for
research applications.  Please find specific product information at

        5.9 Austral Biologicals, Inc, San Ramon, CA. - Antibodies for
research applications.
Please visit our web site: http://www.australbio.com

        6       ELECTRONIC CONTACTS:
6.1     Check out the DNA Repair Interest Group web site:
You can find the schedule for future DNA Repair Interest Group
videoconferences and a listing of past videoconferences (with links to the
videoarchive) as well as a current list of JOB OPPORTUNITIES in DNA repair

6.2     Encourage your colleagues who are interested in DNA Repair to
request that they be added to this DNA Repair Interest Group listserve
e-mail list by sending a request by e-mail to: listserv at list.nih.gov
Leave the subject  blank. In the message field, type in: subscribe
DNARepair-L your name
        Alternatively, by filling out the form on the website
(http://www.nih.gov:80/sigs/dna-rep/ ) you can both add your name to the
e-mail list and have your name posted on the website.  If you want your
name to be listed you can fill out the "Join the SIG" form on the web site
and add your name to the listing of members.  If you are not at NIH then
be sure to click the "other" box and then fill in the name of your

6.3     Archives of these listserve mailings can be found at
        http://list.nih.gov/archives/dnarepair-l.html  or via links from
the DNA Repair Interest Group web site:

6.4     I will be happy to relay information about post-doctoral
positions, jobs and meetings and other information related to DNA Repair.
Please send me an e-mail message (kraemerk at nih.gov) and I will incorporate
it into the next announcement list and post it on the DNA Repair Interest
Group web site: http://www.nih.gov:80/sigs/dna-rep/ .
(This list goes to nearly 1100 scientists around the world who are
interested in DNA repair.)

Kenneth H. Kraemer, M.D.
Chief, DNA Repair Section
Basic Research Laboratory
National Cancer Institute
Building 37 Room 3E24
Bethesda,  MD 20892
301-496-9033    FAX: 301-496-8419
e-mail: kraemerk at nih.gov
DNA Repair Interest Group web site:

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