IUBio

Anything new on the low-level exposure front?

Kristofer Dale barefoot at nmia.com
Fri Sep 29 15:03:40 EST 2000


Joseph Bachman wrote:

> One of the links on the bionet.toxicology FAQ is to something called
> "Biological Effects of Low-Level Exposure" (BELLE), which has introduced
> me to the provocative concepts of things like non-linear  dose-response
> curves, J and U shaped dose-response curves and hormesis.  This stuff
> could, it seems to me, change the way regulators might approach their
> jobs, but from the tone of the stuff in the BELLE newsletters, some of
> this is still pretty cutting edge, if not controversial.  But I'm
> interested in keeping an eye on the current research.  The stuff at the
> BELLE site is a year or more old.  Are there any other places on the Web,
> or certain journals where I can find stuff?

        http://www.vitaletherapeutics.org
 
> And don't worry, they're not expecting me to practice toxicology at
> work, :-)  they want my input on ground water stuff, but some of these
> issues are closely related to whether or not we need to be worried about
> the toxicity of a particular compound.  Anayway, when we do talk toxic
> effect, I'd like to at sound intelligent.

Judging by the minute amounts of biochemical "signals" that regulate immune,
development and metabolic processes, there is good reason to look into the
problem of low-level contamination interfering with or destroying these basic
biological functions both in wildlife and human populations. Be forewarned,
this is a proverbial "can of worms". Big business and big government routinely
send out their top guns to obfuscate the issue and/or deny there is a problem,
the issue of endocrine disruptors being an example...

                              Kristofer Dale,
                              ragged individualist,
                              statistic at large...







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