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Q: Dose response curves and EC50's

Jude Grimley grimley at SOL.CMS.UNCWIL.EDU
Mon Mar 17 14:49:27 EST 1997

I am looking for an alternative to simple linear regression analysis 
for calculating EC50 values from a dose-response curve, specifically 
methods which may identify and/or compensate for outliers.

My primary concern is for maintaining consistency with results from other 
related research, so any suggestions of sources that contain standardized 
techniques for statistical analysis dose response curves (EPA databases?) 
would be greatly appreciated.  


Jude Grimley
Department of Biology
University of NC at Wilmington
(910) 962-3847
grimley at sol.cms.uncwil.edu

"Toxicologists do it until they're half-dead."

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