Arsenic has been shown to cross the placental barrier (as most chemicals).
The total amount of arsenic in a fetus with a mother with high Arsenic
levels tends to increase during gestation. High doses of inorganic
arsenic compounds given to pregnant experimental animals produced several
malformations in fetuses. However, no such effects have been seen in
humans with excessive occupational exposures to arsenic compounds.
Nevertheless, Arsenic poisoning can lead to death of the mother and/or the
fetus from fever, anorexia, melanosis, and cardiac arrhythmia. Anemia,
sensory loss, mucous irritation, and gastrointestinal distress also may
accompany arsenic poisoning. The dose for these symptoms to occur is from
70 to 180 mg ingested by the mother.