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Helminths and corticosteroids

Russell Farris tryggvi at email.msn.com
Sat Jul 31 15:52:09 EST 1999

Is the abstract below saying that Ascaris suum creates cortisol? Are there
other parasites that do so? Thanks,

Russ Farris
Parazitologiia 1977 Jul-Aug;11(4):321-5
[Studies of the corticosteroid hormones in the nematode, Ascaris suum].
[Article in Russian]
Gerasimova NG, Leutskaia ZK
Four steroids from tissues of Ascaris suum were isolated and identified by
means of the thin-layer chromatography and fluorimetric methods as
corticosterone, cortisol, alodosterone and dehydrocorticosterone.
Corticosterone, cortisol and alodosterone are corticosteroid hormones while
dehydrocorticosterone is a product of a metabolic transformation of
corticosterone. It seems likely that the presence of corticosteroid hormones
in tissues of A. suum is indicative of their participation in the metabolism
of the latter.

PMID: 896275, UI: 77256066

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