IUBio Biosequences .. Software .. Molbio soft .. Network News .. FTP

Dientamoeba Fragilis

Gerald L. McLaughlin, Ph.D gmclaugh at iupui.edu
Wed Oct 21 10:10:40 EST 1998


Jackie-

Some of the more extensive studies suggesting that Dientamoeba infections
are asymptomatic have been done in Australia, so I'm not surprised that
Australian MD's think that this is not the cause of your illness.  You are
right that failure to reach statistical correlations between symptoms and
infection, does not preclude the cause of symptoms for a given individual.
Briefly, most studies suggesting non-pathogenicity lack information about
the strain(s) of Dientamoeba, relevant genotypes and environmental factors
that may affect the severity of infection and disease.  For instance
generally, a high fiber diet is bad for intestinal parasites and good for
the patient, and many "non-pathogens" make good pathogens given an
immunocompromised status.  Dientamoebiasis is quite treatable.  When a
patient is symptomatic for some time, I believe that treatment is
warrented, if for no other reason than to reliably remove this potentially
confounding factor.  

Clinicians who believe traditional dogma about "non-pathogens" have needed
a wake-up call for some time; parasitologists and other infectious disease
experts are at least partly to blame for vague thoughts about
"commensalism" and "well-adapted parasites".  Dientamoebiasis is one of
many infections that should be treated and/or prevented. IMO, Trichomonas,
Toxoplasma, Giardia, Candida and similar human-adapted fungi, Chlamydia
pneumoniae and similar bacteria, viruses like papillomavirus, EBV,
hepatitis virus, CMV and other herpesviruses, and other infectious agents
should also be better controlled.  Pasteur's germ theory of disease needs a
dust-off and up-dating to furnish neurobiologists (MS is caused by herpes
virus 6), GI specialists (Helicobacter; and perhaps Dientamoebia), heart
specialists (Chlamydia), pulmonologists (a variety of bacteria and
viruses), who have essentially not learned that both chronic and acute
disease can be induced by infectious agents.

I suspect you can find at least one Aussie MD to treat you as easily as one
from England or the US.  Keep in mind, however, that this does not exclude
other common causes of your illness.

Jerry   
At 06:07 PM 10/20/98 -0700, Jackie wrote:
>Can anyone help.....I live in Sydney, NSW, Australia, and I'm trying to
>find someone who's been successfully treated for Dientamoeba Fragilis. 
>All specialists and doctors I've consulted (and I've seen quite a few
>over the 5 years I've been infected with this parasite) don't take this
>parasite seriously enough to treat it.  I've just done a lot of
>research at our local university medical library and found info. on DF
>which largely refutes the informationt I've been given by the medical
>profession. According to many articles I've found in such journals as
>American Journal for Diseases in Children, Journal of Tropical Medicine
>and Hygiene and others, is that it IS a pathogen (ie it can cause quite
>severe symptoms in some people ranging from weight loss, vomiting,
>blood in the stool, diarrhea/constipation, headaches, nausea, anorexia,
>abdominal pain, fever, fatigue etc),  it is more prevalent than thought
>but goes undetected due to incorrect testing procedures (stool samples
>need to be in some kind of preservative as the parasite doesn't last
>longer than a couple of hours outside of its host.  Also lab. staff
>have to be trained to recognise this particular parasite), and
>metronidazole (Flagyl) isn't always successful but diiodohydroxyquin
>(Diodoquin, Yodoxin etc) has worked in every case.
>
>If anyone would like copies of the articles (I'm condensing them down
>into a manageable size) please email me.  I'm collecting more
>information and intend to get as much information out as possible to
>the medical profession and anyone else suffering from mysterious bowel
>diseases (usually diagnosed as IBS).  I've been (and am) very sick from
>this parasite and there must be many others out there who are in the
>same position as me by not being taken seriously by the medical
>profession and unable to get treated successfully.
>
>In the meantime if anyone can help with a good doctor - please let me
>know - I'm desperate and thinking of travelling to the UK to get
>treated!!!
>
>
>
>
>
Gerald McLaughlin, Ph.D.
Associate Professor
Dept Pathology and Laboratory Medicine
635 Barnhill Drive, MS A128
Indianapolis, IN  46202-5120
317-274-2651; FAX 317-278-2018
E-mail:  gmclaugh at iupui.edu



More information about the Parasite mailing list

Send comments to us at biosci-help [At] net.bio.net