IUBio Biosequences .. Software .. Molbio soft .. Network News .. FTP

(help)sarcosporidiae !!!

William Reeder "wmr-60 at ix.netcom.com" at popd.ix.netcom.com
Tue Jul 28 18:34:10 EST 1998

Thomas Dingfelder wrote:
> Hi everyone !!!
> Could you send me some information on sarcosporidiae?
> I would like to know something about the pathogenity ,
> symptoms of an infestation with sarcosporidiae
> and treatment in human medicine.
> Thanks a lot , Dingi

Sarcosporidiae is an obsolete term.  Replace it with Sarcocystidae and it 
is much easier to find information.  Members of this group are coccidian 
parasites and two genera within the group infect humans, Sarcocystis and 
Toxoplasma. I assume you are asking about Sarcocystis.  Depending upon 
the species involved, humans can act as either intermediate hosts or 
definitive hosts.

When humans act as intermediate hosts, the organism forms cysts in muscle 
tissue (both skeletal and cardiac).  An old term for these cysts is 
Miescher's tubules.  There are at least 7 morphological type of cyst 
found in humans, each presumably is a due to a different species of 
Sarcocystis, although they are often referred to as "Sarcocystis 
lindemanii"  Generally there is no indication of the infection, 
occasionally there may be some local muscle soreness.  Specific treatment 
has not been studied, nor is it needed for the muscle infection.  Only 
about 40-50 cases have been reported in the medical literature, mostly 
from Asia.

There are two species, for which humans act as the definitive host.  
Sarcocystis hominis has a life cycle involving man and cattle and 
Sarcocystis suihominis has a life cycle involving man and swine.  humans 
acquire the infection from ingesting the cysts in muscle tissue from one 
of these two sources.  They both produce an identical disease which 
begins approximately 6 hours from the time of ingestion of the meat.  
Symptoms include bloating, nausea, vomiting, abdominal pain, diarrhea and 
fever.  The symptoms usually last no longer than 24 to 48 hours.  The 
disease appears more severe in immunocompromised persons but the number 
of reported cases is small.  Again there is no recommended specific 
treatment for this infection.  Intestinal sarcocystosis appears to be 
most common in Europe.

I have not gone into great detail into the life cycle, morphology, 
laboratory diagnosis, etc... if you have any other question let me know.

More information about the Parasite mailing list

Send comments to us at biosci-help [At] net.bio.net