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Monensin and Malaria

DR M SANYAL msanyal at medinst.ernet.in
Sun Oct 19 10:54:50 EST 1997

I am working on monensin ,a carboxylic ionophore.It is known to have antimalarial 
activity.Can anyone give some information about maximum tolerable dose(mtd) of
monensin in  swiss albino mice? Has anyone worked with liposomal monensin?If so,
please answer th following questions? Why do these liposomes aggregate? What it 
the mtd of liposomal monensin in swiss albino mice?

Thank you in advance for your time and advice.

Ms. Suparna Dutt========================================================
Department of Biochemistry,
University of Delhi( South Campus)
Benito Juarez Road, 
New Delhi - 110021,

Tel : 91-11-6112159
Fax : 91-11-6885270

e-mail : sup at dusc.ernet.in

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