[Neuroscience] Help with series resistance and EPSP variations

Jeffrey Lopez via neur-sci%40net.bio.net (by jeffrey.yaime from googlemail.com)
Fri Nov 23 17:36:59 EST 2012

Hi everybody, there is a question I have since some time but still
dont have a convinvcing answer.
When your series resistance changes during a patch clamp experiment,
1- which influence does it have on my EPSP slope and amplitude?
3-how would it help or not to use a discontinuous (switching) amplifier?
 If anyone could help me to understand I will appreciate it, please
try to be explicit in answering. Thanks a lot in advance!

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