On Fri, 27 Oct 2006 08:50:04 +1000, Matthew Kirkcaldie
<m.kirkcaldie from removethis.unsw.edu.au> wrote:
>In article <ehqgcn$9r7$1 from mailhub227.itcs.purdue.edu>,
> "Fijoy George" <tofijoy from yahoo.co.in> wrote:
>>> In fact, I am a student (in
>> Computer Science) currently working on the EEG/MEG neural source imaging
>> problem, and I wanted to know how to correctly simulate activation patches
>> on the cortical surface.
>>I sympathise with your problem! Unfortunately I think there's little
>available guidance to suggest a "correct" way, because we don't know
>what kinds of neuronal activity produce fMRI signal. Are you wanting to
>map the electrical EEG domain to the fMRI domain? That sounds like an
>interesting problem and I will have a dig around to see what I can turn
>up. Maybe Dr Agmon or Dr Norman could suggest some resources. My first
>thought is the Brain Dynamics group here in Sydney, Australia - they
>have produced models of EEG power spectra based on simple anatomical
>properties of bulk cortical tissue. I don't think they have applied it
>to correlation with fMRI though - although the members do use fMRI in
>experimental contexts.
>>http://www.brain-dynamics.net/>>Hope that helps - it's much easier to know how to advise when you say
>what you're trying to achieve!
>
It's rather out of my own experience, but you could start with
Nikos K. Logothetis, Jon Pauls, Mark Augath, Torsten Trinath and Axel
Oeltermann
Nature 412, 150-157 (12 July 2001)
"Neurophysiological investigation of the basis of the fMRI signal"
http://www.nature.com/nature/journal/v412/n6843/abs/412150a0.html
Jueptner M, Weiller C
"Review: does measurement of regional cerebral blood flow reflect
synaptic activity? Implications for PET and fMRI."
Neuroimage. 1995 Jun;2(2):148-56.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9343597&dopt=Citation
Arien J. Smith , Hal Blumenfeld , Kevin L. Behar , Douglas L. Rothman
, Robert G. Shulman , and Fahmeed Hyder
"Cerebral energetics and spiking frequency: The neurophysiological
basis of fMRI "
PNAS | August 6, 2002 | vol. 99 | no. 16 | 10765-10770
http://intl.pnas.org/cgi/content/abstract/99/16/10765
David Attwell and Costantino Iadecola
"The neural basis of functional brain imaging signals"
TRENDS in Neurosciences Vol.25 No.12 December 2002
http://people.hnl.bcm.tmc.edu/jli/reference/5.pdf
S. Sheth, M. Nemoto, M. Guiou, M. Walker, N. Pouratian, A. Toga
"Linear and Nonlinear Relationships between Neuronal Activity, Oxygen
Metabolism, and Hemodynamic Responses"
Neuron, Volume 42, Issue 2, Pages 347-355
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15091348&dopt=Abstract
Robert G. Shulman1, Douglas L. Rothman1,2, Kevin L. Behar3 and Fahmeed
Hyder
"Energetic basis of brain activity: implications for neuroimaging"
TRENDS in Neurosciences Vol.27 No.8 August 2004
http://fcm.uncu.edu.ar/3-Posgrado/bases_moleculares/shulman%202004.pdf
P M Matthews and P Jezzard
Functional magnetic resonance imaging
Journal of Neurology Neurosurgery and Psychiatry 2004;75:6-12
http://jnnp.bmjjournals.com/cgi/content/abstract/75/1/6
There is a lot more, but these, plus the references in them, will keep
you busy for a while.
