IUBio

DC lesion?

k p Collins kpaulc at [----------]earthlink.net
Sat Feb 14 01:18:33 EST 2004


"Klenow" <bakedbeans at spam.not> wrote in message
news:PxiXb.9020$%h1.7659 at fe24.usenetserver.com...
>
> I've recently read a paper looking at the effects of 15 minutes of direct
> current stimulation (5-15 uA) through a chronic indwelling electrode on
> kindled seizure thresholds in rats.  Can this type of stimulation cause an
> electrolytic lesion at the electrode tip even with such low current?  I've
> been looking through brain stimulation books and can't find an answer.
>
> --
> -----

I don't know about a resultant lesion,
but the neural architecture is just like
any other machine. It's 'engineered'
to function as it's engineered to func-
tion, and 15 'minutes' of DC is con-
trary to everything that's 'engineered'-
in-there.

Stick a screw driver in the works of
a grandfather clock, or in the spokes
of a bycycle that's riding by - same-old,
same-old.

In the neural architecture, what happens
is that the DC desynchronizes the 'norm-
ally exquisitely-synchronized ["Type II]
neural dynamics. The result is exactly-
analogous to 'stripping-the-gears' of
any machine's mechanism.

ken [k. p. collins]





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