>>>Also how could things like Adrafinil (norepinephrine agonist) work? Is
>>it stored in vesicules at the end of axons together with the
>>norepinephrine and released into the synapses together with it?
> Not stored. Diffusion. Diffusion. OK?
Explain "diffusion" to a layman please?
Does it leak out of the brain vessels and spreads into all the synaptic
clefts roughly equally? (I don't know how this could be helpful: seems
to add just random "noise" to brain signals...?)
...and then is it reabsorbed in the vessels when the concentration of
the agonist in the vessel becomes lower (liver has worked) than the
concentration in the synaptic clefts?