Hi all,
I have read some stuff about neurology over the internet. There is one
thing I don't understand about the synaptic communication:
A neuron releases a neurotransmitter in the synapse to communicate with
another neuron. Now the second neuron is stimulated and active until
the re-uptake clears up the neurotransmitter from there, is this correct?
How much time does it take for the re-uptake mechanism to clear up
everything? I suppose it should be something in the order of magnitude
of seconds, otherwise an old idea/reasoning wouldn't go out of our mind
and we wouldn't be able to think to something else, correct?
In this scenario, what is the purpose of the re-uptake inhibitors? To
confuse our minds by making the old reasonings last in our mind for
hours instead of seconds?
Also how could things like Adrafinil (norepinephrine agonist) work? Is
it stored in vesicules at the end of axons together with the
norepinephrine and released into the synapses together with it?
Is it subject to the same re-uptake as the norepinephrine or it stays in
the synaptic cleft for a long time until slowly goes to the plasma? (if
latter: it would cause roughly the same effect of a reuptake inhibitor,
right?)
TIA