Hi Everybody:
I am confused with EPSP and EPSC(Excitatory Post Synaptic
Potential/Current). Specifically:
I saw a formula to describe an excitatory synapse stimulation effect: i
= G * (v-e); G = weight * exp(-t/tau); i(nA synaptic current),
G(microSiemns synaptic conductance), e(mV reversal potential), tau(mS
decay time constant), weight(synaptic weight), v(mV membrane potential).
Since e is constant, so i is determined by G and v. G is keeping
chaning: G decays with tau; I think v is keep changing due to the inflow
i, am I right? So i does not decay with a single time constant, am I
right? What i trace will looks like?
If weight is increased, i will be increased. How about EPSP? Will it be
increased too?
Maybe some questions are not reasonable. But you can see I am very
confused. Thank you very much for your help. I greatly appreciate it.
Best Regards,
Xiaoshen