Not neccasarily (althought I'm rapidly stepping out of my depth)... What
if there were type II/III mGluRs? Thats what I was originially thinking
of, monoaminergic synapses and metabatropic receptors. (apart from in the
case of GABA)
Matthew Kirkcaldie <Matthew.Kirkcaldie at removethis.newcastle.edu.au> wrote
in news:Matthew.Kirkcaldie-D60CEF.13043217122003
@seagoon.newcastle.edu.au:
> In article <3FDFB0A3.4B1D74 at shaw.ca>, SeeBelow at SeeBelow.Nut wrote:
>>> Which suggests that these autapses are likely to be inhibitory, but I
>> don't believe that's necessary.
>> The assertion that they implement negative feedback would suggest they
> were inhibitory, but in the case of glutamatergic cells (most cortical
> neurons) they aren't inhibitory, and hence do not implement negative
> feedback.
>>>Does anyone know whether most of them
>> are inhibitory?
>> There are no large-scale surveys of autapses that I know of - the
> difficulty of identifying a synapse as autaptic is immense. Hence most
> of the material I have seen is in cultures, and descriptions of
isolated
> examples in vivo.
>> Matthew.
>