i got this from one of my mailing lists....
This month, we bring you news of five new titles on metabolic
engineering, expression technology, malaria, RT-PCR, and prions.
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METABOLIC ENGINEERING IN THE POST GENOMIC ERA
Editors: Boris N. Kholodenko and Hans V. Westerhoff of the Thomas
Jefferson University, Philadelphia USA and BioCentrum Amsterdam, The
Netherlands
Publisher: Horizon Bioscience
ISBN: 0-9545232-2-9
Publication date: 01 January 2004 (Available now!!!)
Price: GB£ 90 US$180
Pages: ix plus 456
Description:
This book aims to help the reader understand and deal with the
plasticity of living cell factories and to turn the plasticity into the
desired
rather than the adverse direction. The book brings together all the
recent, most important breakthroughs in this exciting field.
Internationally renowned scientists review each topic in detail. The editors
provide
an overview of new approaches and describe what the engineer and the
industry may now aim for, even adapting the definition of metabolic
engineering to befit the post-genomics era. Other topics covered: the
experimental approaches necessary to understand cellular regulation at all
of
its hierarchical levels, including proteomics, metabolomics and
fluxomics; new tools that help metabolic engineering; modeling of living
cells; and the optimization of cell factories as production organisms. A
useful chapter on future perspectives directs further developments of the
field in the near future. Essential reading for everyone with an
interest in engineering living cells including: Metabolic engineers,
geneticists, microbiologists, bioengineers, biotechnologists, molecular and
system biologists, and pharmaceutical and biotechnology companies.
http://horizonpress.com/met
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PROTEIN EXPRESSION TECHNOLOGIES: CURRENT STATUS AND FUTURE TRENDS
Editor: François Baneyx of the Department of Chemical Engineering
University of Washington, Box 351750, Seattle, WA 98195, USA
Publisher: Horizon Bioscience
ISBN: 0-9545232-5-3
Publication date: April 01, 2004
Price: GB£ 90 US$180
Pages: c. x + 534
Description:
Advances in protein expression technologies have mushroomed in recent
years. In this book internationally renown authors comprehensively
review current and emerging expression technologies. Detailed reviews of the
molecular genetics of expression systems in various organisms are
presented. Topics covered include: Expression of extremophilic proteins;
expression in E. coli, Bacillus spp., Saccharomyces cerevisiae, and
methylotrophic yeasts; insect cell expression and the baculovirus system;
and
Chinese Hamster Ovary (CHO) cell lines for large-scale protein
production. Also covered are two emerging expression systems,
Methylobacterium
extorquens AM1 and Caulobacter crescentus. An essential reference, this
book will enable both new and experienced expression technologists to
make educated choices on the technology that is best suited for their
needs.
http://horizonpress.com/exp
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MALARIA PARASITES: GENOMES AND MOLECULAR BIOLOGY
Editors: Andrew P. Water and Chris J. Janse of Leiden University
Medical Centre, Leiden, The Netherlands.
Publisher: Caister Academic Press
ISBN: 0-9542464-6-2
Publication date: March 01, 2004
Price: GB £115 US $230
Pages: c. 500
Description:
The completion of the Plasmodium falciparum genome sequence in late
2002 hearlded a new era in malaria research. The search began in earnest
for new drugs and vaccines to combat malaria, a disease which afflicts
up to 500 million people worldwide and is responsible for the deaths of
more than one million people each year. The new genomic data is aiding
a greater understanding of the living parasite and it's interaction
with the insect vector and human host. In this book internationally renown
experts provide up-to-date reviews of the most important aspects of
post-genomic malaria research. Topics covered include: the P. falciparum
genome and model parasites, bioinformatics and genome databases,
microsatellite analysis, analysis of chromosome structure, cell cycle to RNA
polymerase I and II mediated gene expression, role of the nuclear
genome, the parasite surface and cell biology, and much more. The book is
essential to all researchers working in this highly topical field and is
recommended reading for scientists in other areas of biology and
medicine.
http://horizonpress.com/hsp/fnew.html
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ADVANCE NOTICE: TWO TITLES COMING SOON!!!
PRIONS AND PRION DISEASES: CURRENT PERSPECTIVES
Editor: Glenn C. Telling
In recent years, research into prions and prion diseases has progressed
at an impressive pace. In this book internationally renown experts
provide an up to date description of the great advances made in our
understanding of prions and prion diseases in recent years. This volume
provides a comprehesive overview of the pathogenesis, molecular biology,
biochemistry, cellular biology, animal models and immunology of prions
and follows from and expands on our highly acclaimed book "Prions:
Molecular and Cellular Biology". The book is essential to all researchers
working in this highly topical field and is recommended reading for
scientists in other areas of biology and medicine.
Coming soon!!!
http://horizonpress.com/hsp/fnew.html
REAL-TIME PCR: AN ESSENTIAL GUIDE
Editors: Julie Logan, Kirstin Edwards and Nick Saunders
Real-time PCR is a powerful and rapid technique for nucleic acid
amplification. The accumulation of specific products in a reaction is
monitored continuously during cycling. This is usually achieved by
monitoring
changes in fluorescence within the PCR tube. This essential manual
presents a comprehensive guide to the most appropriate and up-to-date
technologies and applications as well as providing an overview of the
theory of this important technique. Written by recognized experts in the
field this timely and authoritative volume is an essential requirement for
all laboratories using PCR. Topics covered include: Real-time PCR
technology and instruments, methods and techniques, controls and
validation, quantitative real-time PCR, analysis of mRNA expression,
mutation
detection, NASBA, application in clinical microbiology and diagnosis of
infection.
Coming soon!!!
http://horizonpress.com/hsp/fnew.html
