Hallo NG,
I have some strange experimental results, which could be explained if
there were something like ion channels which are membrane voltage gated
AND mechano-sensitive at the same time.
I mean is it possible that mechanical stress on the cell membrane, like
a pipette in cell-attached, could lead to the opening of more
voltage-gated channels underneath the patch with the same given voltage
step than normally? That way that the conductance could be something
like 5 - 10 fold for that little peace of membrane?
Excuse the maybe simple question, I'm a technician, not a physiologist.
And have to do this diploma thesis by next tuesday.
Thnx Edmund