Ok ! thanks, Richard and Brian !
So it can take quite a while for the transmitters to go accross the synaptic
cleft.
It is that delay I was 'thinking' about.
For a single synapse, could this delay vary a lot with time ? Or does it just
attempt to match the right delay to work properly for that synapse's function ?
Is there a relation between that delay and the time period during which the
transmitters are caught by the target neuron ? That might depend on the amount
of transmitters, no ?
And does the type of transmitters affect the time it takes to go accross the
synaptic cleft ?
Laurent, as a kid in front of nature.
Thalamus wrote:
> Bon soir Laurent,
> Sorry for putting my .02 ? in here.
>> "Laurent" <lorseau at ens.insa-rennes.fr> skrev i melding
> news:3D34371D.EDB8F929 at ens.insa-rennes.fr...> > Thanks a lot.
> > Anyway, I may have not explain correctly what I wanted, or I don't
> > understand well enough what you say.
> >
> > I have some basic notions about neurons and chemistry, but I haven't tried
> > to know the whole phenomena of the synapse.
> >
> > Here is what I wanted know if it was possible :
> >
> > Neuron A is activated since a few msec (or less or even more).
> > Neuron A suddenly desactivates.
> > Wait some msec.... (delay, no signal in A's axon, nor through Synapse S)
> > Synapse S from neuron A (still desactivated) to neuron B then transmits a
> > signal.
>> Yes, and Richard said so,no ?
> Neuron A activates a _potential_; ae electrical signal that courses through
> the axon (which is the output from the neuron) to the end-terminal (where
> the neurotransmitters are stored in vesicles [containers]).
> Then this signal activates intake of Ca+ (Calsium), which releases vesicles
> (small containers) with neurotransmitters inside them - those vesicles
> 'integrates' then with the cellular membrane and the neurotransmitters are
> released outside of the cell.
> Then it takes some time for these neurotransmitter to diffuse across the
> synaptic cleft (the distance between the terminal of neuron A, and the
> cellular wall of neuron B) were it activate _reseptors_ on neuron B.
> The time it takes from when the signal activates the intake of Ca+ to the
> release of the vesicles is very short.
> And Richard thinks of the time for the neurotransmitter to _diffuse_ from
> neuron A to neuron B; while you are thinking of the time-delay from when the
> signal _activates_ the Ca+ intake.
> Chemically it is the neurotransmitter which is interesting if you are
> searching for a delay, so he gave you the right answer.
> Hope I have helped clearifying things, Laurent.
>> Brian
