IUBio

Increased blood flow detected by fMRI scans?

Brian zhil at online.no
Sun Oct 28 13:39:02 EST 2001


"Richard Norman" <rsnorman at mediaone.net> skrev i melding
news:e9iottkgf1j0vj0d1v6qgn9r39foc11ld4 at 4ax.com...
> On Sun, 28 Oct 2001 15:25:13 +0100, "Brian" <zhil at online.no> wrote:
> I am well aware that CREB-1 (ala Kandel) is well established as a
> major player in long-term plasticity in neurons).  However, I believe
> you did write (no doubt as a jocular suggestion): "If you can find a
> way to increase the production of CREB-1, you'll solve most
> problems.".  Since CREB-1 is involved in a LOT of process besides the
> neuronal one you mention, increasing CREB-1 is also likely to cause a
> lot more problems.  It would be interesting to find a technique to
> selectively stimulate something like CREB-1 in only a particular
> subset of cells.  Targetting the response is a real problem, though.

Well, if we talk about genetic engineered viruses - the problem should be
solvable, don't you think ?
One problem with vectors are their accuracy; will it target the right
cell(s).
So, we could in theory circumvent the whole issue this way.
As I mentioned to Yan, the patch-clamp techniques to integrate electronics
and neuron(s)/ganglia(groups of neurons) are the old techniques - the far
more elegant solution would be to reprogram the neuron to addapt towards the
electronic interface.
I suggested that the patch-clamp tech. would come within the next decade,
but will be released shortly after that, from 2014-2020 by
vector-programming.
Why do I take the aspect of programming so (blatantly) easily ?
I have myself programmed in machine-code (6 years ago) - could it possibly
be more difficult if we follow the ground-rules set by microbiology
(chemical bonds etc.)?
As I see it, scientists are for finding those rules by which nature
operates, while techies will do the dirty work of actually DO the stuff
(they aren't as well paid as the former, so it's cheaper to do it this way).
Anyway, I'm not saying programming is easy, because it certainly isn't !!

Brian





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