IUBio

You Must Remember This

Brian zhil at online.no
Sun Oct 21 19:33:02 EST 2001


"Bob" <bbruner at uclink4.berkeley.edu> skrev i melding
news:3bd334e9.18829718 at agate.berkeley.edu...
> On Mon, 15 Oct 2001 01:56:23 +1000, Michael Jameson
> <m.jameson at hunterlink.net.au> wrote:
>
> >The paper that is the main focus of the article is "DNA recombination as
> >a possible mechanism in declarative memory" by Sandra Pena de Ortiz and
> >Yuri Arshavsky, Journal of Neuroscience Research, vol 63, p 72 (2001).
>
> Ok, I have looked at that paper. It is rather vague, but intriguing.
> Those who want to consider the questions the poster raised should read
> it.
>
> The basic idea they suggest is that memory storage may involve somatic
> recombination, as with immunoglobulin genes. They provide evidence,
> both from the known literature and from their new work, that somatic
> recombination is "possible" or even "likely" in the nervous system.
>
> The proposal does lead to some predictions that are presumably open to
> testing, so it does seem like a constructive proposal. One could
> rephrase the proposal... what is the role of enzymes of somatic
> recombination in the nervous system?
>
> Some of the objections raised in this thread are irrelevant. For
> example, is reverse transcription (RT)  a problem. No, nothing in
> their proposal requires RT (and if it did, I'm sure the cell could
> come up with some). Discussions of roles for junk DNA are essentially
> irrelevant, since there is no clear need for any particular amount of
> DNA.
>
> bob

Thank you Bob,
That cleared things somewhat.
So, basically the long term meories are stored as molecules in the cytoplasm
?

Brian





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