IUBio

neuroscience lab

SA nospam at nospam.net
Wed May 23 04:16:15 EST 2001


In article <9edmkj$7go3 at imsp212.netvigator.com>,
 "yan king yin" <y.k.y(at)lycos(dot)com> wrote:

> "Constantine Mihailidis" <conmih at tin.it>:
> > Hi,  my name is Constantine Mihailidis and I am a med student at the "La
> > Sapienza" University of Rome. I am fascinated by neuroscience and your ideas
> > about possible research on neuroimplants. Do you maintain something like a
> > newsletter to keep interested persons informed. Nevertheless, although you
> > may find this funny I would like to join your group (if you ever create
> > one...) and help by my side in any way I can...
> 
> You're very welcome =)  I was also thinking to start a mailing list, i'll
> post it here soon.  Not many people had inquired though.
> 
> My earlier concept of conducting experiments on-line is not so sound.  But
> it might be possible to open labs locally while sharing the expensive
> instruments on-line.  Some samples have to be refrigerated so i dont know
> how feasible is that.
> 
> At first, I had the idea of making the neuro-interface.  Then I found that
> it would be nice to open those "self-help" laboratories as well.  The two
> things are different and i hope its not too confusing.  Please stay tuned,
> and email me anytime if you have questions or suggestions.

I think the private "core facility" concept is unsound. There are 
several reasons, I will be short, though:

1. major universities already put these cores in place, for expensive or 
low use, or very technical equipment, e.g., fMRI, microscopes confocal 
or EM, dna microarrays, transgenic injection facilities, etc. They are 
also relatively easy to establish, universities in general like core 
facilities.

2. they are extreme money-losing operations. Getting the equipment is 
not a big deal, it is usally easy to get a grant for this kind of thing, 
since funding agencies, and university dean's love core facilities. the 
problem is staffing it, which requires several faculty members part time 
and several technicians.  plus the equipment becomes obsolete very fast 
whcih means someone, almost always a faculty member, spends significant 
amount of time getting more equipment (grant writing, making meetings 
with people etc). fees associates with cores usually do not cover the 
actual costs, but are heavily subsidized by the university. the 
reasoning is they are recovering 60% in indirect costs off other grants 
you can sustain because you have access to the core and keep publishing 
and so on, so it is in their interest. By the way, they get no overhead 
on these "equipment' grants from funding agencies.

3. even then core facilities get low utilization in my experience, 
people tend to want to run experiments in their own labs or with trusted 
collaborators. Most people find that people do a better job when they 
have a specific scientific interest in the project.  I would personally 
rather go to a collaborator across the country than to a core facility 
on campus, even in the same building as I am, and I have before.

4. the big problem you would have is:
 1. you wouldn't quality or be able to get most federal grants
 2. people wouldn't pay the value since they could establish thier own 
core: unless,
 3. you had special expertise not available anywhere else. Some companies
   have done well offering specialized tests at specific rates. That is
   they do not attempt to provide a lab, but just certain things they do 
    very well.
 4. you wouldn't be able to find cheap staffing

not to say I think you can do "business" in neuroscience, just not the 
way you are proposing.




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