what is cycloheximide's mechanism?

666 y.k.y at lycos.com
Sat Mar 17 15:17:45 EST 2001

"cycloheximide -- inhibits the peptidyl transferase activity of the 60S
ribosomal subunit (in eukaryotes)."
-- p903,"Antibiotics induce miscoding and block peptide-bond formation
and translocation", Biochemistry, 4th Ed, Lubery Stryer (1995)

hope this helps =)

>   we know that cycloheximide will inhibit protein sythesis,
>   then affect our memory,but what is its detailed mechanism?

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