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SSRI questions....Can anyone answer these, preferably a doc or student?

Mark D. Morin mdmpsyd at PETERHOOD69.earthlink.net
Wed Mar 7 05:54:42 EST 2001


anxiety man wrote:
> 
> SSRIs.
> 
> Are they safe?
> 
> problem #1 ... caused abnormalities in the brain cells of rats.
> 
> http://www.drugtext.org/press/webster/mar00/%5B%5D%20Serotonin-Boosting%20Drugs%20Cause%20Changes%20In%20Some(Peter%20Webster).htm
> 
> Brain Research (March 6, 2000).  Vol. 858, 92-105
> 
> How serious should we take this????


at 10-30 times the therapeutic dose almost any substance is
going to have negative effects.

> 
> problem #2 ... Questioning of the mechanism of action and possible
> negative action.
> 
> http://www.geocities.com/HotSprings/3568/ATracyPhD.htm ..... go to:
> LATEST MEDICAL DOCUMENTATION REVEALS THESE SERIOUS PROBLEMS *and*
> SEROTONIN - THE KEY TO THE PSYCHADELIC EXPERIENCE:
> .....


This one does a good job of distorting some pieces of fact
and presenting them in a scare tactic format.  I'd print out
the page and bring it in to your doctor.

> 
> I am at a personal crossroads. I've been trying to figure out the best
> way to treat my stress disorder in which I manifest physical symptoms
> from anxiety. I was prescribed Zoloft but after Paxil did not work and
> reading all this it seems that I should only work with a therapist....

Given the efficacy of psychotherapy for both depression and
anxiety, yeah--maybe you should be working with a
psychotherapist.

> 
> How much truth is in this "anti-SSRI" stuff?


Mr. "Anti-SSRI" is a nut case living in NJ, on a personal
vendetta against the world because his ex-wife (a
psychiatrist) was awarded custody of their son.  Take
whatever he says with several grains of salt.

> I know that my chances of
> Zoloft helping me aren't great anyway (6 in 10 vs 5 in 10 on placebo).
> 
> What do neurologists think about the two "problems" I outlined.

neuropsychologist not neurologist and I don't consider them
to be problems.

> 
> Are Anne Blake Tracy, Peter Breggins, and some of the other "anti-SSRI"
> docs (a) "kooks" or (b) is this stuff "legit"?

stick with (a)

> 
> I.E. Do you think SSRIs cause brain damage or adversely affect the
> brain.
> 
> Any and all answers are appreciated.
> 
> Thank you,
> AM (wish to remain anonymous)


-- 
===============================================================
Every day I walk myself into a state of well being and walk 
away from every illness. I have walked myself into my best 
thoughts, and I know of no thought so burdensome that I
cannot 
walk away from it. 

               Soren Kierkegaard (1813 - 1855) 
               Philosopher and theologian 

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