here is my thoughts on the situation,
the ressults are due to the use of SAM and not SAM-e,
if SAM-e was to cause depletion of those NT's then I doubt It would have an
antidepressent effect, however i do recall tom matthews saying something
about high doses of SAM-e causes parkinsons symptoms.
However, the psychoactive effects of TMG have not been evaulated and i would
consider it guilty until proven innocent.