IUBio

blood cells enter the cerebrospinal fluid

Dan-solo dotoole at NOSPAM!tcd.ie
Tue Oct 5 07:36:37 EST 1999


>In article <7t9fd4$4cq at news.acns.nwu.edu>, "MJ Lee" <mjlee at nwu.edu> wrote:
>
>Can blood cells pass through BBB and enter the cerebrospinal fluid?
>thanks!
>
.
Blood resident lymphocytes can break through the BBB during a Multiple
Sclerosis relapse, where they are directed to inflammation sites by IL-10.
I don't think this normally ever happens though. As far as I know,
macrophages can do the same thing. I'd imagine that any oxygen required by
the neuron is provided via the  astrocyte, as there are no RBCs in CSF.



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