rcb5 at MSN.COM ("Ron Blue") wrote (7389, 29 Mar 1999)
>[Uric acid as a scavenger in oxidative stress]
>VERNACULAR TITLE: A hugysav jelentp6ege az antioxidacios vedelemben.
>AUTHORS: Staub M
>AUTHOR AFFILIATION: Orvosi Vegytani, Molekularis Biologiai es Patobiokemiai
>Intezet, Semmelweis Orvostudomanyi Egyetem.
>SOURCE: Orv Hetil 1999 Feb 7;140(6):275-9
>CITATION IDS: PMID: 10071505 UI: 99170899
flefever at ix.netcom.com(F. Frank LeFever) wrote (7396, 30 Mar 1999)
>Hmmm... I have a vague impression I may have challenged you to produce
>such a reference, and here it is! Provocative. Hungarian, is it?
>Will forward this to my work email as a reminder to look into it
>further.
Ron's point is supported by the following recent publication, which covers
very similar ground to the ?Hungarian paper cited above:
Uric Acid In EAE & Multiple Sclerosis
-------------------------------------------------------------------
Hooper DC, Spitsin S, Kean RB, Champion JM, Dickson GM,Chaudhry I,
Koprowski H, Proc Natl Acad Sci U S A 1998 Jan 20;95(2):675-680
UI # 9435251
Thomas Jefferson University,
Center for Neurovirology,
Department of Microbiology and Immunology,
Philadelphia, PA 19107-6799
USA
Abstract at:
http://www.geocities.com/HotSprings/3468/uric_acid-peroxynitrite2-98.html
What is intriguing me is why only uric acid? i.e., if the uric acid is
being depleted by oxidative stress, why are not other anti-oxidants
depleted also?
Alan.
Dr. Alan Wheatley at http://www.canadalane.demon.co.uk