I knew you'd say "I knew it"...
In <#q3p8yX2#GA.276 at cpmsnbbsa05> "Ken Collins" <KPaulC at email.msn.com>
writes:
>>i knew it was glutamate all along, Frank, but glutamate was referenced
in
>one of the refs i read in response to the work John's doing... so,
since
>folks knew i was 'over-there', i didn't bother.
>>my earlier ref to kainic acid was a reference back to a series of
>presentations i gave at Smith College back in the 80s.
>>excitotoxicity is excitotoxicity... the nervous system 'moves away
from'
>such... glutamate is in-there, but it's normally well-controlled,
except
>when lesions disrupt the intact mechanism, as in strokes or epilepsy.
>>all of this is in AoK, Frank, if you'd 'just' =Think=, instead of
'moving
>away from'...
>>...guess AoK's just a bit to 'exciting' for you to deal with :-)
>>K. P. Collins
>>F. Frank LeFever wrote in message
<7nokep$cvf at dfw-ixnews6.ix.netcom.com>...
>>>>Maybe I should put it more simply: it is really not relevant whether
>>10% or 100% of all the known and unknown neurotransmmitters are "in"
>>AoK, implicitly or explicitly; the point is, you do not have the most
>>basic UNDERSTANDING of them, and by your foolish rush to say
something
>>you thought was relevant demonstrated that you do NOT know WHICH
>>excitatory amino acid is involved in NATURALLY OCCURING neurotoxic
>>reacttions due to seizure, stroke, or mechanical trauma.
>>>>By now, you should have had time to look it ups. (NOT in AoK, of
>>course; but if you think it's in there, by all means look again; if
you
>>find it, tell us what it is.)
>>>>F. LeFever
>>>>>>>>In <utVGgqy1#GA.421 at cpmsnbbsa02> "Ken Collins" <KPaulC at email.msn.com>
>>writes:
>>>>>>i stand on what i posted...
>>>>>>every neuro-active substance that exists, or which can be
artificially
>>>synthesized, is thoroughly discussed in AoK.
>>>>>>K. P. Collins
>>>>>>F. Frank LeFever wrote in message
>><7ngk0i$j3e at dfw-ixnews14.ix.netcom.com>...
>>>>>>>>What a pathetic clutching at a pretense of knowing something:
>>>>"implicit", oh, yeah...
>>>>>>>>You would have been better off if you had left it implicit, but
>>>>NO-o-o-o: you had to throw in a word you had read somewhere (as
>>usual,
>>>>without understnding the context at all). At about the time you
>>>>stopped reading, kainic acid was all the rage for EXPERIMENTALLY
>>>>INDUCED lesions, but surely you MUST know (QUICK, re-read AoK, it
>>MUST
>>>>be in there SOMEWHERE--maybe next to the missing fornix section?),
>>MUST
>>>>know that when people are talking about ENDOGENOUS OVERPRODUCTION
due
>>>>to seizure or stroke or trauma. they are talking about SOME OTHER
>>>>excitatory amino acid; one which is very important in normal
>>>>functioningf; indeed, one which is the neurotransmitter in perhaps
>>90%
>>>>of the brain's synapses (well, don't flame me if I am off by 1 or 2
>>>>percentt).
>>>>>>>>Enough hints? I won't say whatt it is until you've had a chance to
>>>>look it up and post it and say "I knew that!"
>>>>>>>>F. LeFever
>>>>>>>>>>>>>>>>>>>>In <uVk4xnk1#GA.252 at cpmsnbbsa05> "Ken Collins"
<KPaulC at email.msn.com>
>>>>writes:
>>>>>>>>>>'excitotoxins'... chemically-induced rampant TD E/I(up, up)... as
in
>>>>'kainic
>>>>>acid'.
>>>>>>>>>>it's all (implicit) in AoK, Frank.
>>>>>>>>>>ken collins
>>>>>>>>>>F. Frank LeFever wrote in message
>>>><7nd3lg$o5a at dfw-ixnews4.ix.netcom.com>...
>>>>>>>>>>>[...]
>>>>>>>>>>>Knowing personally someone who has played a very important role
in
>>>>>>establishing the role of excitotoxins in hippocampal damage due
to
>>>>>>seizure, and giving considerable attention to the role of
>>>>excitotoxins
>>>>>>(i.e. over-produced excitatory amino acid transmitters) in other
>>>>>>conditions (stroke, head trauma),
>>>>>>>>>>>[...]
>>>>>>>>>>>>>>>>>>>>>>>>
