IUBio

RETRACTION...

Ken Collins KPaulC at email.msn.com
Tue Jul 27 11:06:38 EST 1999


I RETRACT THIS EARLIER POST OF MINE... i'll explain elsewhere.

K. P. Collins

Ken Collins wrote in message ...
>the press release didn't provide sufficient info, but simply inducing and
>'LTP'-like condition indiscriminantly with respect to the
>topologically-distributed nature of 'normal' nervous system function, does
>not eliminate all of the trophic consequences inherent in the
>non-interfered-with resultant activation 'state', and if there's enough
>information remaining in the resultant activation 'state' to allow the TD
>E/I-minimization mechanisms to achieve convergence upon a supersystem
>configuration, the nervous system ('brain') does exactly that, and an
>'appropriate' behavioral response is 'addressed' via the TD
E/I-minimization
>with respect to what's left, 'after' the experimental stuff is 'applied'.
>
>within the tightly-integrated neural topology, the forced,
>indiscriminant-of-the-TD, 'LTP'-like condition, in fact, constitutes a
>relatively-random activation sub-'state'... a TD E/I(up) sub-'state'... and
>any remaining (non-interfered-with) TD E/I-minimization mechanisms just
>'whittle' (AoK, Ap5) it away, as they 'normally' do with with other
>superfluous (relatively-random) activation.
>
>it's been a major shortcoming of most experiments in Neuroscience that the
>tight mapping of the neural topology has been largely ignored... if an
>experimental design is not engineered in a way that keeps the Topology of
>the experimental part commensurate with the innate neural Topology, then,
to
>the degree of such, the experiment yields False results.
>
>K. P. Collins
>
>John wrote in message <933043969.298961 at server.australia.net.au>...
>>
>>"There still remains, however, one unresolved and very controversial
issue:
>>To what extent does long-term potentiation participate in learning and
>>memory acquisition? Contrary to their expectations, the scientists from
>>Heidelberg could not demonstrate abnormal learning behaviour in the mutant
>>mice. Rather, the mice lacking LTP were, like normal mice, capable of
>>accurately finding a submerged, invisible platform in a pool of murky
water
>>("water maze") and to swim there immediately when placed in the water."
>>
>>
>>
>>
>>
>>http://www.eurekalert.org/releases/mpg-dal060299.html
>>
>>
>
>





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