Taking a look at my email, etc., after a two-week stay in South Africa
(neuropsych meeting in Durban, delivering photos of Chief Luthuli to
his home village, ETC.), so maybe this is too little and too late, but
obviously the changes are not permanent. They put me on cold-turkey
caffeine withdrawal when hospitalized on emergency basis a couple of
years ago (long story, but included atrial fibrillation). Only now,
when I take an OCCASIONAL cup of coffee (i.e. not my previous habitual
3 or 4 mornings and evenings) can I tolerate those wimps who say "Oh,
just decaf for me, I need to sleep tonight!" (indeed, I have become one
of them!)
F. LeFever
In <Pine.SOL.3.96.990630123550.28926A-100000 at gol> Ralph Leonhardt
<leo at neuroinformatik.ruhr-uni-bochum.de> writes:
>>>On Wed, 30 Jun 1999, Dave Moore wrote:
>>...snip...
>> What I'm trying to find out is
>> whether these new receptors are permanent, or whether the brain has
the
>> ability to deconstruct them so to speak.
>...snip...
>>Hi Dave,
>>my guess would be, that the cells sort of recycles the non-functional
or
>superfluous receptors, just as they do with other proteins. I think
they
>try to keep the level of functional units at an optimal level, which
is
>why they synthesize new receptors in the first place. For the exact
>mechanisms maybe refer to a cell physiology text book.
>>> I have been spending countless sleepless nights researching
>> a question that has been bothering me for years and i just can't
seem to
>> find the answer to this question. I had read that methylxanthines
>> get their effect by blocking the adenosine receptors in the brain.
Also
>> that the brain responds by manufacturing more adenosine receptors to
>> compensate for the ones that are being blocked and inoperative.
>...snip...
>> It really bothers me that everytime I drink a cup of coffee or tea I
may
>> be permanently altering my brain physiology.
>>Maybe you should cut back on coffee/tea if you spend so many sleepless
>nights, so that your brain physiology can adjust to a normal level ;-)
>>Greetings, Leo
>