In <77329t$27$1 at hercules.iupui.edu> "RAS" <raspinel at iupui.edu> writes:
>>>F. Frank LeFever wrote in message
<77197t$8rm at sjx-ixn4.ix.netcom.com>...
>>Follow-up: because the assertion that lidocaine had no known side
>>effects was made so matter-of-factly, I thought I should check
current
>>status of MY view of local anesthetics.
>>I probably should have clarified that to read "at dosages used in
>dentistry." I realize there are side effects, but they are
dose-dependent.
>>
Also, perhaps, individual-dependent? The rest of my post included
references to relevance of individual history variations, e.g. prior
history of cocaine use, which could lower thresholds.
There may be other sources of individual variation as well--not only
historic (besides cocaine use, what about mild traumatic brain injury?
cf. Nils Varney et al.), but perhaps genetic also?
Perhaps SOME individuals may experience side effects even at normal
dentistry doses...
F. LeFever