Follow-up: because the assertion that lidocaine had no known side
effects was made so matter-of-factly, I thought I should check current
status of MY view of local anesthetics. Quick Medline search via Ovid
disk confirms seizure provocation by this class of anesthetics
(cocaine, lidocaine, procaine) is still alively field of investigation.
New and socially-relevant findings: synergistic (not overlapping nor
even additive, but synbergistic) effect of cocaine and lidocaine in
this "side effect". ALSO: cross sensitization, such that history of
cocaine use may potentiate lidocaine seizure provocation...
(To my disappointment, did not find anything in this recent time frame
on lidocaine etc. and PARTIAL seizures)
F. Frank LeFever, Ph.D.
New York Neuropsychology Group
In <76uodn$367 at sjx-ixn9.ix.netcom.com> flefever at ix.netcom.com(F. Frank
LeFever) writes:
>>>I question the assertion that lidocaine has no known side effects.
See
>my ref in previous post to partial-seizure-like effects of local
>anesthetics in this general class.
>>F. LeFever
>>>>In <76r97q$kig$1 at hercules.iupui.edu> "RAS" <raspinel at iupui.edu>
writes:
>>>>>Brian, I think what Joel was getting at was that the sterile water
was
>>simply a placebo that also caused vaso-vagal syncope. The
"spaciness"
>that
>>these patients experienced was likely due to worrying about the
>needle! I
>>typically get "spacey" after any shot that I get (except in the
>mouth)--I've
>>even passed out 10 minutes after a Hepatitis B vaccination. I
>consider it a
>>psychogenic reaction--I remember sitting there worrying if the
vaccine
>could
>>possibly give me Hepatitis B! Same with flu shots and TB tests.
>However,
>>when I get a local anesthetic, I am fine--probably because I'm more
>aware of
>>what it is, how it works, and how harmless it is. Having said that,
>there
>>are rare side effects to mepivacaine that could explain those
>feelings.
>>However, lidocaine has no known side effects (other than if someone
is
>>allergic to all amide-type anesthetics).
>>>>Ray
>>>>>>>>>: Can also be due to an injection of anything including sterile
water
>in
>>>: a patient with very low blood pressure and a low tolerance for
this
>>>: kind of stuff.
>>>>>>>
