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ischemic insults

Richard Goodwin libiengoodwin at mindspring.com
Thu Aug 19 18:24:28 EST 1999


I'm interested in comparing the severity of insults used in several stroke
models.  If the insults are of similar duration, which would cause the most
damage?  which the least?

bilateral carotid occlusion
cardiac arreest
4 vessel occlusion
middle cerebral artery occlusion

how do these compare to anoxia/ aglycemia in hippocampal slices or in
primary cultures?
which in vivo insult would be closest to anoxic slices?

what about to glutamate or NMDA toxicity?

Any info would be greatly appreciated.

Thanks!

Jenny





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