Bob--
Is it really possible? That he heard "CREB" and thought Krebs?? But
whence "cycle" ? Maybe he had studied Krebs cycle years ago and was
thereby primed to hear CREB as kreb??? Possible. But I find it hard
to believe that Kandel would have said he intended to market a pill in
10 years (or ever). And yet, and yet... Columbia has invested a lot
in its new biotech/commercial facilities (where Malcom X was shot)...
(Did you really see this program, or is this just an inspired guess?)
F. Frank LeFever, Ph.D.
New York Neuropsychology Group
In <73h39k$atl$1 at usenet01.srv.cis.pitt.edu>
mihalek at FORMULA1.smtp.anes.upmc.edu (Robert M. Mihalek) writes:
>>In article <365B5480.3A47 at one.net>
>Mike <roboart at one.net> writes:
>>> I saw a show on the Discovery Channel last week (Nov 15-Nov 20)
about
>> memory.
>> It had a article on a doctor named "kandell" (not sure about
spelling)
>> who was doing reseach on the krebs cycle in rodents. Apparently he
was
>> having success in helping older rats improve their memory by using a
>> substance(drug) he developed. It was said that he intends to market
the
>> substance as a pill in the next 10 years.
>> Also in a seperate part of the same show was a article about a man
named
>> HM who had amnesia for the past 30-40 years after a surgery.
>>Dr. Eric Kandel at Columbia University in New York City is the man.
The
>research in question is about a class of proteins called cyclic AMP
>response-element binding proteins: CREB. These proteins have been show
>to activate gene transcription in vertebrates and invertebrates
>following specific types of training procedures designed to induce
>long-term memory formation.
>>>Bob Mihalek, Ph.D.
>University of Pittsburgh School of Medicine
>Department of Anesthesiology/CCM
>
