> From: Marcello Spinella <optimism32 at hotmail.com>
> Organization: EarthLink Network, Inc.
> Subject: Parkinson's disease and rigidity
> If Parkinson's disease involves rigidity, why isn't baclofen
> effective to treat it?
Perhaps because Parkinson's rigidity is a dopamine-related
symptom and baclofen is a B-GABAergic agonist.
The fact that baclofen is an antispastic is insignificant:
What seems the same symptom can be produced by different
breakdowns (eg. haemophilia).
Renato Cocchi MD