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Calea zacatechichi

Claude de Contrecoeur cyrano at pasdemerde.touic.comu
Mon Jun 16 07:13:52 EST 1997


Other Formats:  [MEDLINE Format]
Links:  [106 medline neighbors]

J Ethnopharmacol 18 (3): 229-243 (1986)

Psychopharmacologic analysis of an alleged oneirogenic plant: Calea

Mayagoitia L, Diaz JL, Contreras CM

Calea zacatechichi is a plant used by the Chontal Indians of Mexico to
obtain divinatory messages during dreaming. At human doses, organic
extracts of the plant produce the EEG and behavioral signs of
and induce light sleep in cats. Large doses elicit salivation, ataxia,
retching and occasional vomiting. The effects of the plant upon
discharge frequency were significantly different from
hallucinogenic-dissociative drugs (ketamine, quipazine, phencyclidine
SKF-10047). In human healthy volunteers, low doses of the extracts
administered in a double-blind design against placebo increased
time and time-lapse estimation. A controlled nap sleep study in the
volunteers showed that Calea extracts increased the superficial stages
sleep and the number of spontaneous awakenings. The subjective reports
dreams were significantly higher than both placebo and diazepam,
an increase in hypnagogic imagery occurring during superficial sleep

MeSH Terms:

   * Adult
   * Analysis of Variance
   * Animal
   * Behavior, Animal/drug effects
   * Cats
   * Diazepam/pharmacology
   * Double-Blind Method
   * Dreams/drug effects*
   * Electroencephalography
   * Female
   * Human
   * Male
   * Mexico
   * Plant Extracts/pharmacology
   * Plants, Medicinal*
   * Psychotropic Drugs*
   * Random Allocation
   * Reaction Time/drug effects
   * Respiration/drug effects
   * Sleep/drug effects*
   * Time Perception/drug effects*


   * Diazepam
   * Plant Extracts

PMID: 3821139, MUID: 87142942


 the above report in  format.


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