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Cortical Architectures

Ken Easlon ken5 at delphi.com
Mon Mar 7 21:04:58 EST 1994

erwin at trwacs.fp.trw.com (Harry Erwin) writes in
<2lcq4g$2v7 at truffula.fp.trw.com>:

> 5. Anyone have a clue as to the function of the cortical
> neurons that use neuropeptide transmitters? 

Thanks for the references.  Here's a paragraph from "Core Text of
Neuroanatomy, 4th edition" author Malcolm B. Carpenter, page 397.

Peptides identified mainly in the cerebral cortex include
cholecystokinin (CCK), vasoactive intestinal polypeptide (VIP), and
neuropeptide Y (NPY).  These peptides are found in superficial
layers close to capillaries and may control local metabolism and
blood flow.  VIP is a potent vasodilator and NPY is a
vasoconstrictor.  Somatostatin-like immunoreactivity in the cortex
is significantly reduced in Alzheimer's disease.

Ken Easlon
ken5 at delphi.com

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