Hi,
I am a Ph.D. student who will be graduating in Spring 1994 from the Dept.
of Physiology, University of Manitoba. I am seeking a post-doctoral
position in the field of Neuroscience. More specifically, I am interested
in Ca2+ homeostasis in neurons and pathophysiological consequences of
aberrations in intraneuronal Ca2+ levels. The techniques that I am
interested in are Ca2+ imaging and electrophysiology. I have extensive
experience in neurochemical methods including receptor binding, enzyme
assays, HPLC, autoradiography and intracellular Ca2+ measurements using
Fura-2. Although I reside in Canada, I have US citizenship. This may allow
me to apply for fellowship awards from US agencies. Furthermore, I am
eligible to apply for a Medical Research Council of Canada Fellowship
(Deadline - November, 1993). If anyone is interested in taking me on as a
post-doc., please contact me as soon as possible. My e-mail address is
rpadum at ccu.umanitoba.ca. I've included my curriculum vitae here as well
and references can be provided upon request. Thanks
CURRICULUM VITAE
BIOGRAPHICAL NOTES
NAME: Rodolfo Alberto Padua
ADDRESS: Department of Physiology, University of Manitoba
Faculty of Medicine, 770 Bannatyne Ave.
Winnipeg, Manitoba R3E 0W3
PHONE: (204) 896-4883 (H)
(204) 789-3454 (W)
(204) 783-6915 (FAX)
DATE OF BIRTH: 7 August 1965
PLACE OF BIRTH: Phoenix, Arizona
CITIZENSHIP: USA (Permanent Resident since July, 1969)
I Scholastic Experience
1988 - Present Ph.D. Department of Physiology
University of Manitoba
Winnipeg, Manitoba
Supervisors: Dr. J.I. Nagy
Dr. J.D. Geiger
1985 - 1988 B.Sc. Biochemistry
(Honours) University of Manitoba
Winnipeg, Manitoba
1983 - 1985 Chemistry
Queen's University
Kingston, Ontario
II Positions Held
1992 - Present Teaching Assistantship
Department of Chemistry
University of Manitoba
Supervisor: Dr. Ann Scoot
1986 - 1992 Teaching Assistantship
Department of Chemistry
University of Manitoba
Supervisor: Dr. G. Hickling
1988 Summer Research Assistantship
Department of Physiology, Faculty of Medicine
University of Manitoba
Supervisors: Dr. J.I. Nagy
Dr. J.D. Geiger
1987 Summer Research Assistantship
Department of Microbiology
University of Manitoba
Supervisor: Dr. H.B. Lejohn
1987 Teaching Assistantship
Department of Biology
University of Manitoba
Supervisor: Dr. L. Graham
III Awards
1985 - 1987 Dean's Honour List
1990 University of Manitoba Studentship Award - declined
1990 - Present Medical Research Council of Canada Studentship Award
1992 Health Sciences Centre Neuroscience Student Research Award
1993 International Society for Neurochemistry Travel Award
1993 University of Manitoba Alumni Association Travel Award
IV Affiliations
1990 - present International Society of Neurochemistry
1990 - present Winnipeg Chapter, Society for Neuroscience
1991 - present Society for Neuroscience
V Refereed Publications
1.Padua R., Geiger J.D., Dambock S., and Nagy J.I. (1990) 2'-Deoxycoformycin
inhibition of adenosine deaminase in rat brain: in vivo and in vitro analysis
of specificity, potency and enzyme recovery. J.Neurochem. 54: 1169-1178.
2.Padua R.A., Wan W., Geiger J.D., and Nagy J.I. (1991) [3H]Ryanodine binding
sites in rat brain demonstrated by membrane binding and autoradiography.
Brain Res. 542: 135-140.
3.Padua R.A, Geiger J.D., Delaney S.M., and Nagy J.I. (1992) Rat brain
adenosinedeaminase after 2'-deoxycoformycin (DCF) administration: biochemical
properties and evidence for reduced enzyme levels detected by [3H]DCF ligand
binding. J. Neurochem. 58: 421-429.
4.Padua R.A., Yamamoto T., Fyda D., Sawchuk M.A., Geiger J.D., and Nagy J.I.
(1992) Autoradiographic analysis of [3H]ryanodine binding sites in rat brain:
regionaldistribution and the effects of lesions on sites in the hippocampus.
J. Chem. Neuroanat. 5: 63-73.
5.Stein M., Padua R.A., Nagy J.I., and Geiger J.D. (1992) High affinity
[3H]ryanodine binding sites in postmortem human brain: regional distribution
and effects of Ca2+, Mg2+ and caffeine. Brain Res. 585: 349-354.
6.Padua R.A., Nagy J.I. and Geiger J.D. (1993) Ionic strength-dependence of
calcium, adenine nucleotides, magnesium and caffeine actions on ryanodine
receptors in rat brain. J. Neurochem. Submitted.
7.Padua R.A., Nagy J.I. and Geiger J.D. (1993) Ryanodine- and
caffeine-sensitive Ca2+ stores in rat brain synaptosomes. In preparation.
VI Book Chapters
1.Geiger J.D., Padua R., and Nagy J.I. (1990) Adenosine deaminase and
adenosine transport systems in the CNS. In: Purines in Cellular Signalling:
Targets for New Drugs, (Eds. K. Jacobson, J. Daly, V. Manganiello),
pp. 20-25. Springer-Verlag, New York.
2.Geiger J.D., Padua R.A., and Nagy J.I. (1991) Adenosine deaminase
regulation of purine actions. In: Adenosine and Adenine Nucleotides as
Regulators of Cellular Function, (Ed. J.W. Phillis), pp 71-84. CRC Press,
Boca Raton, Florida.
VII Abstracts
1.J.D. Geiger, R. Padua, L.T.Y. Wong, and J.I. Nagy (1989). Adenosine
Deaminase and Transport Systems in the CNS. Dialog Science Research
Symposium on "Purine Nucleosides and Nucleotides in Cell Signalling: Targets
for New Drugs", Sept. 17-20, Rockville, Maryland.
2.R. Padua, J.D. Geiger, S. Dambock and J.I. Nagy (1989). 2'-Deoxycoformycin
Inhibition of Adenosine Deaminase in Rat Brain: Specificity, Dose
Dependency, and Enzyme Recovery. 19th Annual Meeting Society for Neuroscience,
Nov. 1989, Phoenix, Arizona.
3.R.A. Padua, W. Wan, J.D. Geiger and J.I. Nagy (1990). Pharmacological
Characterization of High Affinity [3H]Ryanodine Binding Sites in Subcellular
Fractions of Rat Brain. 20th Annual Meeting Society for Neuroscience,
Nov. 1990, St. Louis, Missouri.
4.R.A. Padua, W. Wan, D. Fyda, T. Yamamoto, M. Sawchuk, J.D. Geiger and J.I.
Nagy (1991). Pharmacology and Cellular Localization of [3H]Ryanodine Receptors
in Rat Brain. 21st Annual Meeting Society for Neuroscience, Nov. 1991,
New Orleans, Louisiana.
5.M.B. Stein, R.A. Padua, J.I. Nagy and J.D. Geiger (1991). High Affinity
[3H]Ryanodine Binding Sites in Postmortem Human Brain. 21st Annual Meeting
Society for Neuroscience, Nov. 1991, New Orleans, Louisiana.
6.R.A. Padua, J.I. Nagy and J.D. Geiger (1993). Ionic Strength-dependence of
calcium, adenine nucleotides, magnesium and caffeine actions on ryanodine
receptors in rat brain. 14th International Society for Neurochemistry,
Aug. 1993, Montpellier, France.
VIII Theses
1.Padua, R. (1988) Molecular cloning, isolation and preliminary restriction
endonuclease characterization of Ras homologous sequences in Achlya klebsiana.
B.Sc. Thesis.
2.Padua, R.A. (1994) Regulation and function of ryanodine receptors in the
CNS. Ph.D. Dissertation. In progress.