Hi,
I am a Ph.D. student who will be completing the program next spring. I am
looking for a post-doctoral position in a neuroscience laboratory. My
current research interest is in the area of intracellular calcium
homeostasis. The project which I am currently working on is the
regulation and function of ryanodine receptors in the CNS. I have
extensive experience in neurochemical techniques including enzyme assays,
receptor binding and autoradiographic methods and calcium measurements
utilizing Fura-2. I would like to get involved in a laboratory that
combines both electrophysiological and calcium imaging techniques. If
there is anyone interested, please contact me. My e-mail address is
rpadum at ccu.umanitoba.ca or I can be reached by phone - (204) 789-3454 or
by fax - (204) 783-6915. I have included here my curriculum vitae to
provide more background information.
CURRICULUM VITAE
BIOGRAPHICAL NOTES
NAME: Rodolfo Alberto Padua
ADDRESS: Department of Physiology, University of Manitoba
Faculty of Medicine, 770 Bannatyne Ave.
Winnipeg, Manitoba R3E 0W3
PHONE: (204) 896-4883 (H)
(204) 789-3454 (W)
(204) 783-6915 (FAX)
DATE OF BIRTH: 7 August 1965
PLACE OF BIRTH: Phoenix, Arizona
CITIZENSHIP: USA (Permanent Resident since July, 1969)
I Scholastic Experience
1988 - Present Ph.D. Department of Physiology
University of Manitoba
Winnipeg, Manitoba
Supervisors: Dr. J.I. Nagy
Dr. J.D. Geiger
1985 - 1988 B.Sc. Biochemistry
(Honours) University of Manitoba
Winnipeg, Manitoba
1983 - 1985 Chemistry
Queen's University
Kingston, Ontario
II Positions Held
1992 - Present Teaching Assistantship
Department of Chemistry
University of Manitoba
Supervisor: Dr. Ann Scoot
1986 - 1992 Teaching Assistantship
Department of Chemistry
University of Manitoba
Supervisor: Dr. G. Hickling
1988 Summer Research Assistantship
Department of Physiology, Faculty of Medicine
University of Manitoba
Supervisors: Dr. J.I. Nagy
Dr. J.D. Geiger
1987 Summer Research Assistantship
Department of Microbiology
University of Manitoba
Supervisor: Dr. H.B. Lejohn
1987 Teaching Assistantship
Department of Biology
University of Manitoba
Supervisor: Dr. L. Graham
III Awards
1985 - 1987 Dean's Honour List
1990 University of Manitoba Studentship Award - declined
1990 - Present Medical Research Council of Canada Studentship Award
1992 Health Sciences Centre Neuroscience Student Research Award
1993 International Society for Neurochemistry Travel Award
1993 University of Manitoba Alumni Association Travel Award
IV Affiliations
1990 - present International Society of Neurochemistry
1990 - present Winnipeg Chapter, Society for Neuroscience
1991 - present Society for Neuroscience
V Refereed Publications
1.Padua R., Geiger J.D., Dambock S., and Nagy J.I. (1990) 2'-Deoxycoformycin
inhibition of adenosine deaminase in rat brain: in vivo and in vitro analysis
of specificity, potency and enzyme recovery. J.Neurochem. 54: 1169-1178.
2.Padua R.A., Wan W., Geiger J.D., and Nagy J.I. (1991) [3H]Ryanodine binding
sites in rat brain demonstrated by membrane binding and autoradiography.
Brain Res. 542: 135-140.
3.Padua R.A, Geiger J.D., Delaney S.M., and Nagy J.I. (1992) Rat brain
adenosinedeaminase after 2'-deoxycoformycin (DCF) administration: biochemical
properties and evidence for reduced enzyme levels detected by [3H]DCF ligand
binding. J. Neurochem. 58: 421-429.
4.Padua R.A., Yamamoto T., Fyda D., Sawchuk M.A., Geiger J.D., and Nagy J.I.
(1992) Autoradiographic analysis of [3H]ryanodine binding sites in rat brain:
regionaldistribution and the effects of lesions on sites in the hippocampus.
J. Chem. Neuroanat. 5: 63-73.
5.Stein M., Padua R.A., Nagy J.I., and Geiger J.D. (1992) High affinity
[3H]ryanodine binding sites in postmortem human brain: regional distribution
and effects of Ca2+, Mg2+ and caffeine. Brain Res. 585: 349-354.
6.Padua R.A., Nagy J.I. and Geiger J.D. (1993) Ionic strength-dependence of
calcium, adenine nucleotides, magnesium and caffeine actions on ryanodine
receptors in rat brain. J. Neurochem. Submitted.
7.Padua R.A., Nagy J.I. and Geiger J.D. (1993) Ryanodine- and
caffeine-sensitive Ca2+ stores in rat brain synaptosomes. In preparation.
VI Book Chapters
1.Geiger J.D., Padua R., and Nagy J.I. (1990) Adenosine deaminase and
adenosine transport systems in the CNS. In: Purines in Cellular Signalling:
Targets for New Drugs, (Eds. K. Jacobson, J. Daly, V. Manganiello),
pp. 20-25. Springer-Verlag, New York.
2.Geiger J.D., Padua R.A., and Nagy J.I. (1991) Adenosine deaminase
regulation of purine actions. In: Adenosine and Adenine Nucleotides as
Regulators of Cellular Function, (Ed. J.W. Phillis), pp 71-84. CRC Press,
Boca Raton, Florida.
VII Abstracts
1.J.D. Geiger, R. Padua, L.T.Y. Wong, and J.I. Nagy (1989). Adenosine
Deaminase and Transport Systems in the CNS. Dialog Science Research
Symposium on "Purine Nucleosides and Nucleotides in Cell Signalling: Targets
for New Drugs", Sept. 17-20, Rockville, Maryland.
2.R. Padua, J.D. Geiger, S. Dambock and J.I. Nagy (1989). 2'-Deoxycoformycin
Inhibition of Adenosine Deaminase in Rat Brain: Specificity, Dose
Dependency, and Enzyme Recovery. 19th Annual Meeting Society for Neuroscience,
Nov. 1989, Phoenix, Arizona.
3.R.A. Padua, W. Wan, J.D. Geiger and J.I. Nagy (1990). Pharmacological
Characterization of High Affinity [3H]Ryanodine Binding Sites in Subcellular
Fractions of Rat Brain. 20th Annual Meeting Society for Neuroscience,
Nov. 1990, St. Louis, Missouri.
4.R.A. Padua, W. Wan, D. Fyda, T. Yamamoto, M. Sawchuk, J.D. Geiger and J.I.
Nagy (1991). Pharmacology and Cellular Localization of [3H]Ryanodine Receptors
in Rat Brain. 21st Annual Meeting Society for Neuroscience, Nov. 1991,
New Orleans, Louisiana.
5.M.B. Stein, R.A. Padua, J.I. Nagy and J.D. Geiger (1991). High Affinity
[3H]Ryanodine Binding Sites in Postmortem Human Brain. 21st Annual Meeting
Society for Neuroscience, Nov. 1991, New Orleans, Louisiana.
6.R.A. Padua, J.I. Nagy and J.D. Geiger (1993). Ionic Strength-dependence of
calcium, adenine nucleotides, magnesium and caffeine actions on ryanodine
receptors in rat brain. 14th International Society for Neurochemistry,
Aug. 1993, Montpellier, France.
VIII Theses
1.Padua, R. (1988) Molecular cloning, isolation and preliminary restriction
endonuclease characterization of Ras homologous sequences in Achlya klebsiana.
B.Sc. Thesis.
2.Padua, R.A. (1994) Regulation and function of ryanodine receptors in the
CNS. Ph.D. Dissertation. In progress.
Thanks in advance,
Rudy
email rpadum at ccu.umanitoba.ca